| ESAD | Eastern Softball Association of the Deaf | 东部聋人垒球协会 |
| ESAD | Empire State Association of the Deaf | 帝国国家聋人协会 |
| ESAD | Electronic Safe and Arm Device | 电子安全和手臂装置 |
| ESAD | Eat Stuff and Die (polite form) | 吃东西死（礼貌用语） |
| ESAD | Escola Superior de Artes e Design (Portugal) | Escola Superior de Artes e Design（葡萄牙） |
| ESAD | Engineering Sciences and Applications Division | 工程科学与应用部 |
| ESAD | Equivalent Still Air Distance (aviation; distance flown, accounting for headwinds or tailwinds) | 等效静止距离（航空；飞行距离，考虑逆风或顺风） |
| ESAD | Earth Science and Applications Division (NASA Hq) | 地球科学与应用部（NASA Hq） |