| HPI | Hydrographic Project Instructions | 水文项目说明 |
| HPI | High-Pressure Injection | 高压喷射 |
| HPI | House Price Index (OFHEO) | 房价指数（OFHEO） |
| HPI | Health Provider Index (New Zealand) | 健康提供者指数（新西兰） |
| HPI | Hydrocarbon Process(ing) Industry | 碳氢化合物加工工业 |
| HPI | Hazard Potential Index | 潜在危险指数 |
| HPI | Human Performance Improvement | 人因绩效改进 |
| HPI | Health Policy Institute | 卫生政策研究所 |
| HPI | Hobby Products International | 爱好产品国际 |
| HPI | Happy Planet Index | 快乐星球指数 |
| HPI | Health Promotion Institute | 健康促进研究所 |
| HPI | Horizontal Production Integration | 横向生产集成 |
| HPI | Host Port Interface | 主机端口接口 |
| HPI | High-Power Illuminator | 高功率照明器 |
| HPI | Heifer Project International (international family self-reliance program) | 国际小母牛计划（国际家庭自力更生计划） |
| HPI | Hermite Polynomial Interpolant | 埃尔米特多项式插值 |
| HPI | Hemera Photo-Object Image | Hemera照片对象图像 |
| HPI | Hogan Personality Inventory | 霍根性格调查表 |
| HPI | Human Performance Institute | 人类行为研究所 |
| HPI | Himpunan Pramuwisata Indonesia | Himpunan Pramuwisata印度尼西亚 |
| HPI | Hewlett Packard Invent | 惠普发明 |
| HPI | Hall Position Indicator (elevators) | 大厅位置指示器（电梯） |
| HPI | High Probability of Intercept | 高截获率 |
| HPI | Horn Plastics, Inc. | 霍恩塑料公司。 |
| HPI | Hasso Plattner Institut | Hasso Plattner研究所 |
| HPI | Human Poverty Index | 人类贫困指数 |
| HPI | human peripheral lymphocyte | 人外周淋巴细胞 |
| HPI | human protein index | 人类蛋白质指数 |
| HPI | High Performance Indicator | 高性能指标 |
| HPI | hepatic perfusion index | 肝脏灌注指数 |
| HPI | Hire Purchase Information | 租购信息 |
| HPI | Heifer Project International | 国际小母牛项目组织 |
| HPI | Having Perfect Intentions | 有完美的意图 |
| HPI | Font information (GEM) | 字体信息（GEM） |
| HPI | High-Pressure Isolation | 高压隔离 |
| HPI | Holes Per Inch | 每英寸孔数 |
| HPI | Hit Points Inflicted | 影响的命中点 |
| HPI | Hybrid Polarization Interferometry | 混合偏振干涉法 |
| HPI | Hurricane Protection Industries | 飓风防护工业 |
| HPI | High Power Illuminator | 大功率照明装置 |