| CREAM | Cosmic Ray Energetics And Mass | 宇宙射线能量学和质量 |
| CREAM | Creators of Rudimental Excellence and Movement (drum corps) | 初级卓越和运动的创造者（鼓队） |
| CREAM | Cosmic Radiation Effects and Activation Monitor (NASA) | 宇宙辐射效应和激活监测器（NASA） |
| CREAM | Christ Rules Everything Around Me | 基督统治着我周围的一切 |
| CREAM | Cash Rules Everything Around Me | 现金支配着我周围的一切 |
| CREAM | Combat Readiness Electromagnetic Analysis Measurement Program | 战备电磁分析测量计划 |