| ACME | Association of Consulting Management Engineers | 顾问管理工程师协会[美] |
| ACME | Arms Control in the Middle East Negotiations | 中东武器控制会谈 |
| ACME | Association for Convention Marketing Executives | 会议营销主管协会 |
| ACME | Association of Consulting Municipal Engineers | 咨询市政工程师协会 |
| ACME | Association for Chinese Management Educators | 中国管理教育工作者协会 |
| ACME | Automated Contractual Minimal Enhancements (Sprint) | 自动化契约最小增强（Sprint） |
| ACME | Advisory Committee on the Marine Environment | 海洋环境咨询委员会 |
| ACME | A Company that Makes Everything | 制造一切的公司 |
| ACME | Assembling Configuration Management Environments (software development) | 组装配置管理环境（软件开发） |
| ACME | American Company that Manufactures Everything | 制造一切的美国公司 |
| ACME | Actively Conserving Marysville Environs | 积极保护马里斯维尔环境 |
| ACME | Advanced Cosmic Microwave Explorer (satellite) | 高级宇宙微波探测器（卫星） |
| ACME | Application of Commercially Manufactured Electronics | 商用电子产品的应用 |
| ACME | Airborne Cloud Measurement Equipment | 机载云测量设备 |
| ACME | Air Crew Combat Mission Enhancement | 空中乘员战斗任务增强 |
| ACME | Authentication Credential Management Extension (authentication subsystem, OpenVMS HP Corporation) | 身份验证凭据管理扩展（身份验证子系统，OpenVMS HP Corporation） |
| ACME | Aerospace, Civil and Mechanical Engineering (department) | 航空航天、土木和机械工程（系） |
| ACME | Applications of Computers to Manufacturing Engineering | 计算机在制造工程中的应用 |
| ACME | Annual Conference of Managing Editors | 总编辑年会 |
| ACME | Adaptive Collection Management Environment | 自适应收集管理环境 |
| ACME | Alumni Council of Middle East | 中东校友会 |
| ACME | Acme Communications | Acme通信 |
| ACME | Action Conflict Mystery And Emotion | 动作冲突神秘与情感 |
| ACME | Amazing Canadian Mountain Expedition | 惊人的加拿大山地探险 |
| ACME | Academic Credit for Military Experience | 军事经验学术学分 |
| ACME | Assembling Configuration Management Environments | 组装配置管理环境 |
| ACME | American Company Makes Everything | 美国公司创造一切 |
| ACME | Activities Committee For Metro Employees | Metro员工活动委员会 |
| ACME | Advisory Committee for Mathematics Education | 数学教育咨询委员会 |
| ACME | Advisory Council on Medical Education | 医学教育咨询委员会 |
| ACME | Annual Creative Marketing Extravaganza | 年度创意营销狂欢节 |
| ACME | Atlanta Chapter Model Education | 亚特兰大分会模范教育 |
| ACME | Anyone Can Make Enemies | 任何人都可以成为敌人 |
| ACME | Athena Competition Mastery And Enrichment | 雅典娜竞赛的掌握和丰富 |
| ACME | Academy of Criminology, Mathematics, and Education | 犯罪学、数学和教育学院 |
| ACME | Anticipate Compensate Meta-cognition Error checking | 预期补偿元认知错误检查 |
| ACME | All Can Modify the Environment | 所有人都可以修改环境 |