| OSO | Orbiting Solar Observatory | 奥索（轨道太阳观测站） |
| OSO | Osoboe Sovescanie Special Commission (Soviet Union, Communism, Stalin) | Osoboe Sovescanie特别委员会（苏联、共产主义、斯大林） |
| OSO | OposiciÓn Sindical Obrera | OposiciÓn Sindical Obrera |
| OSO | Office of Security Operations | 安全行动办公室 |
| OSO | Orbiting Solar Observatories | 轨道太阳观测站 |
| OSO | Onsala Space Observatory | 昂萨拉太空观测站 |
| OSO | Other Significant Others | 其他重要其他 |
| OSO | Ottawa Symphony Orchestra (Canada) | 渥太华交响乐团（加拿大） |
| OSO | Office of Systems Operations | 系统运营办公室 |
| OSO | Outperform Stock Options | 表现优于股票期权 |
| OSO | Office of Satellite Operations | 卫星运营办公室 |
| OSO | Objectives & Strategies Overview | 目标和策略概要 |
| OSO | Operational Support Officer | 业务支助干事 |
| OSO | Other Supply Officer | 其他供应官员 |
| OSO | Operating System Office | 操作系统办公室 |
| OSO | OstsÜdost | OstsÜdost |
| OSO | Oxfordshire Schools Orchestra (UK) | 牛津郡学校管弦乐队（英国） |
| OSO | Ordnance Supply Office | 军械供应处 |
| OSO | Operational Support Office | 运营支持办公室 |
| OSO | Office of SIGINT Operations | 信号情报行动办公室 |
| OSO | Office of Systems Operations (Social Security Administration) | 系统运营办公室（社会安全管理局） |
| OSO | Operations Staff Officer | 运营参谋 |
| OSO | Ordnance Safety Observer | 军械安全观察员 |
| OSO | Office of Satellite Operations (US Department of Commerce, NOAA) | 卫星运营办公室（美国商务部，NOAA） |
| OSO | Office of Space Operations (NASA) | 太空操作办公室（NASA） |
| OSO | Organizational Security Officer | 组织安全干事 |
| OSO | Offensive Systems Operator | 进攻性系统操作员 |
| OSO | Order Sending Organization (NASD) | 订单发送组织（NASD） |
| OSO | Ovest-Sud-Ovest (Italian: West-South-West) | Ovest Sud Ovest（意大利语：West South West） |
| OSO | Office of Systems Operations (NOAA, Silver Spring, MD) | 系统操作办公室（NOAA，Silver Spring，MD） |
| OSO | Office of Signals Operations (US CIA) | 信号作战办公室（美国中央情报局） |
| OSO | OverScan Operation (VXA Technology) | 过扫描操作（VXA技术） |
| OSO | OstsÜdost (German: East-South-East) | OstsÜdost (German: East-South-East) |
| OSO | Other Significant Other | 其他重要其他 |
| OSO | Officer Selection Office | 军官选拔办事处 |
| OSO | Om Shanti Om (Bollywood movie) | Om Shanti Om（宝莱坞电影） |
| OSO | Ontario Special Olympics (Canada) | 安大略省特殊奥运会（加拿大） |