| ESN | Electronic Serial Number | 电子序号 |
| ESN | Enterprise Storage Network | 企业存储网络 |
| ESN | Emergency Service Number | 紧急服务号码 |
| ESN | european society of neuroradiology | 欧洲神经放射学学会 |
| ESN | Energy Sciences Network (Sprint) | 能源科学网络（Sprint） |
| ESN | European Singularity Network | 欧洲奇点网络 |
| ESN | Eldor Spinal Needle | 接骨针 |
| ESN | Equipment Serial Number (cellular) | 设备序列号（蜂窝式） |
| ESN | Electrical Symbol Number | 电气符号编号 |
| ESN | educationally subnormal | 教育程度低于正常水平 |
| ESN | estrogen-stimulated neurophysine | 雌激素刺激的神经生理学 |
| ESN | european society of nematologists | 欧洲线虫学家学会 |
| ESN | English-Speaking Nation | 英语国家 |
| ESN | Enterprise Social Networking | 企业社交网络 |
| ESN | Electronic Sports Network | 电子体育网络 |
| ESN | Elysian Space Navy (Honor Harrington science fiction novels) | 爱丽西亚太空海军（荣誉哈灵顿科幻小说） |
| ESN | European Securities Network | 欧洲证券网 |
| ESN | Erasmus Student Network | 伊拉斯谟学生网络 |
| ESN | Electronic Signage Network | 电子标牌网络 |
| ESN | European Services Network | 欧洲服务网络 |
| ESN | Erasmus Student Network (Europe) | 伊拉斯谟学生网络（欧洲） |
| ESN | Earthstewards Network | 地球管家网络 |
| ESN | Essential Services Node | 基本服务节点 |
| ESN | EOSDIS Science Network | EOSDIS科学网络 |
| ESN | Educationally Sub-Normal (UK) | 教育程度低于正常水平（英国） |
| ESN | Electronic Solutions Now | 电子解决方案现在 |
| ESN | Electronic Switched Network | 电子交换网络 |
| ESN | Entertainment and Sports Network | 娱乐和体育网络 |
| ESN | Engineering Services Network | 工程服务网络 |