| DDO | Departmental Duty Officer | 部门值班员 |
| DDO | Deputy Director of Operations (US CIA) | 行动副主任（美国中央情报局） |
| DDO | Digital Dental Office | 数字牙科办公室 |
| DDO | Device Driver Overlay | 设备驱动程序覆盖 |
| DDO | Digital Data Out | 数字数据输出 |
| DDO | District Directorate Officer | 地区首长级官员 |
| DDO | Designated Days Off | 指定休息日 |
| DDO | Discrete Digital Output (NASA) | 离散数字输出（NASA） |
| DDO | Dynamic Decision Ordering | 动态决策排序 |
| DDO | Disk Drive Overlay | 磁盘驱动器覆盖 |
| DDO | Double Die Obverse (numismatics) | 双骰子正面（钱币学） |
| DDO | Dominion Drop Out | Dominion辍学 |
| DDO | Designated Detention Officer (UK police) | 指定拘留官（英国警察） |
| DDO | Designated Detention Officer | 指定拘留官 |
| DDO | Disobeying a Direct Order | 不服从直接命令 |
| DDO | Direct Dialing Overseas (Nortel) | 海外直拨（北电） |
| DDO | Dynamic Drive Overlay | 动态驱动器覆盖 |
| DDO | Dollard des Ormeaux (Montreal District) | Dollard des Ormeaux（蒙特利尔区） |
| DDO | Dungeons & Dragons Online | 地下城和龙在线 |
| DDO | Digital Data Objects | 数字数据对象 |
| DDO | Duty District Officer | 值班区官员 |
| DDO | Data Dictionary Object | 数据字典对象 |
| DDO | Doubled Die Obverse | 双面模具正面 |