| HFS | the Hartford Food System | 哈特福德食品系统 |
| HFS | Hierarchical File System | 麦金塔阶层式档案系统 |
| HFS | HyperFine Structure | 超精结构 |
| HFS | Hrvatska Udruga Filmskih Snimatelja (Croation Cinematographers Society) | Hrvatska Udruga Filmskih Snimatelja（克罗地亚电影摄影师协会） |
| HFS | Hardware Friendly Software | 硬件友好型软件 |
| HFS | Hamel Flying Saucer | 哈梅尔飞鱼 |
| HFS | High Fidelity Stereo | 高保真立体声 |
| HFS | hydroceic funiculi spermatici | 精索索积水 |
| HFS | Hagfors, Sweden | 瑞典哈格福斯 |
| HFS | Hardware Functionality Scan | 硬件功能扫描 |
| HFS | Hectare Furrow Slice | Hectare沟片 |
| HFS | Hi-Fi Stereo | 高保真度立体声 |
| HFS | High Fructose Syrup | 高果糖糖浆 |
| HFS | HTTP File Server | HTTP文件服务器 |
| HFS | Hierarchical Filing System | 分级归档系统 |
| HFS | Health Food Shop | 健康食品店 |
| HFS | Housing And Food Services | 住房和食品服务 |
| HFS | HyperFine Shift | 超精细移位 |
| HFS | Health and Family Services | 健康和家庭服务 |
| HFS | Australian Department of Health and Family Services | 澳大利亚卫生和家庭服务部 |
| HFS | Housing Finance System | 住房金融系统 |
| HFS | Hartree-Fock Slater (Calculations for Arbitrary Temperature and Matter Density) | Hartree Fock Slater（任意温度和物质密度的计算） |
| HFS | Hot Finished Seamless (European Pipe Standards) | 热加工无缝钢管（欧洲管道标准） |
| HFS | High Fantasy Society | 高幻想社会 |
| HFS | Hemifacial Spasm | 半面部痉挛 |
| HFS | Hospital Formulary System | 医院处方系统 |
| HFS | Health Food Store | 保健食品店 |
| HFS | Higher Frequency Subband | 高频子带 |
| HFS | Hydrogen Forward Scattering | 氢正向散射 |
| HFS | Human Factors Society | 人因社会 |
| HFS | High Fidelity Simulator | 高保真模拟器 |
| HFS | Hot Fuel Storage | 热燃料储存 |
| HFS | Healthcare Facilitation Services | 医疗保健促进服务 |
| HFS | Heritage Family Study | 遗产家族研究 |