| PFO | Paphos, Cyprus - International (Airport Code) | 塞浦路斯帕福斯-国际（机场代码） |
| PFO | Paphos, Cyprus | 塞浦路斯帕福斯 |
| PFO | Preferred Income Opportunity Fund | 优先收入机会基金 |
| PFO | Pacific Food Outlook | 太平洋食品展望 |
| PFO | Parent Facility Organization | 上级设施组织 |
| PFO | Pre Field Orientation | 现场前方向 |
| PFO | Plutonium Finishing Operation | 钚精加工操作 |
| PFO | Please Frig Off (polite form, as in a PFO letter for a refused resume) | 请拒绝（礼貌的形式，如PFO信中拒绝的简历） |
| PFO | Pyruvate:Ferredoxin Oxidoreductase | 丙酮酸盐：铁氧还原酶 |
| PFO | Principal Federal Official (US Departement of Homeland Security) | 主要联邦官员（美国国土安全部） |
| PFO | Paint Flag Offset (marking underground utilities) | 绘制标志偏移（标记地下公用设施） |
| PFO | Project Formulation Office (NASA) | 项目制定办公室（NASA） |
| PFO | Pinyon Flat Observatory (earthquake reporting station) | Pinyon Flat天文台（地震报告站） |
| PFO | Power Fail Output | 电源故障输出 |
| PFO | Persistent Foramen Ovale (cardiology) | 持续性卵圆孔（心脏病学） |
| PFO | Property and Fiscal Office | 财产和财政办公室 |
| PFO | Pissed Fell Over (UK medical slang for drunk patient) | 撒尿跌倒（英国医学俚语，指醉酒患者） |
| PFO | Patent Foramen Ovale (defect of the heart) | 卵圆孔未闭（心脏缺陷） |
| PFO | Profit From Operations | 运营利润 |
| PFO | Patent Foramen Ovale | 福拉门奥瓦尔专利 |
| PFO | patent foramen ovale(cordis) | 卵圆孔未闭 |
| PFO | Perron-Frobenius Operator | Perron Frobenius算子 |
| PFO | Parent Faculty Organization | 家长教师组织 |
| PFO | Personal Freedom Outreach | 个人自由外展 |
| PFO | Positive Feedback Only | 仅正面反馈 |