| OPEN | One Planet Education Network | 一个星球教育网络 |
| OPEN | Oregon Public Education Network | 俄勒冈州公共教育网 |
| OPEN | Oncovin, Prednisone, Etoposide, Novantrone | Oncovin、泼尼松、依托泊苷、诺文特龙 |
| OPEN | Online Public Education Network | 在线公共教育网络 |
| OPEN | Origins of Plasma in the Earth's Neighborhood | 在地球上的起源的等离子体的左邻右舍 |
| OPEN | Optical Pan-European Network | 泛欧洲光学网络 |
| OPEN | Olympic and Paralympic Employment Network (UK) | 奥林匹克和残奥会就业网络（英国） |
| OPEN | Open Protocol Enhanced Networks | 开放协议增强网络 |
| OPEN | Olympic and Paralympic Employment Network | 奥运会和残奥会就业网络 |
| OPEN | Object-Oriented Process, Environment, and Notation (OPEN Consortium) | 面向对象的过程、环境和符号（OPEN Consortium） |
| OPEN | Open-Car Pleasure and Entertainment Network | 开放式汽车娱乐网络 |
| OPEN | Online Park Enrollment Network | 在线公园注册网络 |
| OPEN | Orphan Pets Enjoy Nature | 孤儿宠物享受大自然 |
| OPEN | Objects, Process, Environment, and Notation | 对象、过程、环境和符号 |