| HDO | High Demand Occupation | 高需求职业 |
| HDO | Homeland Defense Office | 国土安全办公室 |
| HDO | High Density Overlay (phenolic resin-impregnated plywood used in concrete forms) | 高密度覆盖层(混凝土模板中使用的酚醛树脂浸渍胶合板) |
| HDO | Humanitarian Demining Operation | 人道主义排雷行动 |
| HDO | Headache During Orgasm | Orgasm期间头痛 |
| HDO | Holy Day of Obligation | 神圣的义务日 |
| HDO | Hearing Designation Order (FCC proceedings) | 听证指定令(FCC程序) |
| HDO | Hydrogen Deuterium Oxide | 氢氘氧化物 |
| HDO | Hispanic Democratic Organization | 西班牙裔民主组织 |
| HDO | Hard Disk Only | 仅硬盘 |
| HDO | Heavy Duty Oil | 重负荷油 |
| HDO | Hunky Dory Organization | Hunky Dory组织 |
| HDO | High Density Overlay | 高密度叠加 |