| HIE | Hietshware | Hietshware软件 |
| HIE | Whitefield, New Hampshire USA | 怀特菲尔德，美国新罕布什尔州 |
| HIE | Herald In Education | 教育先驱 |
| HIE | Holidays In Eden | 伊甸园假期 |
| HIE | Health Insurance Experiment | 健康保险实验 |
| HIE | Hypoxic Ischemic Encephalopathy | 缺氧缺血性脑病 |
| HIE | Holiday Inn Express | 快捷假日酒店 |
| HIE | Highlands and Islands Enterprise | 高地和岛屿企业 |
| HIE | HipertensiÓn Inducida por el Embarazo (Spanish: Pregnancy-Induced Hypertension) | HipertensiÓn Inducida por el Embarazo (Spanish: Pregnancy-Induced Hypertension) |
| HIE | Health Informatics Europe (journal) | 欧洲健康信息学（期刊） |
| HIE | hypoxic-ischemic encephalopathy | 缺氧缺血性脑病 |
| HIE | Hyperimmunoglobulin E-Recurrent Infection | 高免疫球蛋白E复发性感染 |
| HIE | human intestinal epithelial(cell) | 人肠上皮（细胞） |
| HIE | hyperimmunoglobulin e | 高免疫球蛋白e |
| HIE | Horney Industrial Electronics (Bridgeville, DE) | 霍尼工业电子（德国布里奇维尔） |
| HIE | Health Insurance Exception | 健康保险例外 |
| HIE | Highlands and Islands Enterprise (Scotland) | 高地和岛屿企业（苏格兰） |
| HIE | Al-Hassan Industrial Estate | Al Hassan工业区 |
| HIE | Hazard Identification and Evaluation (more commonly abbreviated HI&E) | 风险识别、评估(一般缩写HI&E) |
| HIE | Elliptical Metal Halide (lighting) | 椭圆金属卤化物（照明） |
| HIE | Health Information Exchange | 健康信息交换 |
| HIE | Health Insurance Enrollment | 健康保险登记 |
| HIE | Host Interface Equipment | 主机接口设备 |