| GIST | Girls Into Science and Technology | 女孩进入科学与技术 |
| GIST | Global Information Systems Technology | 全球信息系统技术 |
| GIST | GNSS In-Service Test (GPS) | GNSS在役测试（GPS） |
| GIST | Gwangju Institute of Science and Technology (Korea) | 光州科学技术学院（韩国） |
| GIST | Graphic Intelligence Support Terminal | 图形智能支持终端 |
| GIST | Gastrointestinal Stromal Tumor | 胃肠道间质瘤 |
| GIST | Generalized Search Tree | 广义搜索树 |
| GIST | Geographic Information Support Team (community of interest of humanitarian geospatial experts) | 地理信息支持小组（人道主义地理空间专家利益共同体） |
| GIST | Georgia Interactive Statewide Telecommunications | 佐治亚州交互式全州电信 |
| GIST | Generic Information Server Toolkit | 通用信息服务器工具包 |
| GIST | Geographic Information System Technician | 地理信息系统技术员 |
| GIST | Gastro-Intestinal Stromal Tumor | 胃肠间质瘤 |
| GIST | Genome Informatics System of Transputers | Transputer基因组信息学系统 |