| LFS | Local fish store | 区域鱼店 |
| LFS | Li-Fraumeni syndrome | Li-Fraumeni综合征 |
| LFS | Logic File System | 逻辑文件系统 |
| LFS | Li-Fraumeni Syndrome (cancer predisposition syndrome) | Li Frauemeni综合征（癌症易感综合征） |
| LFS | Lead Foot Syndrome | 铅足综合征 |
| LFS | Licensed Financial Services Division | 持牌金融服务部 |
| LFS | Live For Speed | 为速度而活 |
| LFS | Littlest Fifi System | 最小的Fifi系统 |
| LFS | liquid free serum | 无液体血清 |
| LFS | limbic forebrain structure | 边缘前脑结构 |
| LFS | liver function series | 肝功能系列 |
| LFS | large fenestra stapedectomy | 镫骨大窗切除术 |
| LFS | Low Floor Systems (bus model) | 低地板系统（总线型号） |
| LFS | Landing Fire Support | 登陆火力支援 |
| LFS | Live for Speed (computer racing simulation) | Live for Speed（计算机赛车模拟） |
| LFS | Load Far Pointer in FS | 在FS中加载远指针 |
| LFS | Libertarian Futurist Society (political foresight group) | 自由意志主义未来主义社会（政治远见团体） |
| LFS | Local Fish Shop | 当地鱼店 |
| LFS | Labour Force Survey (UK) | 劳动力调查（英国） |
| LFS | Laser Fence Sensor | 激光围栏传感器 |
| LFS | Linux from Scratch | Linux从零开始 |
| LFS | Lower Frequency Subband | 低频子带 |
| LFS | Local File System | 本地文件系统 |
| LFS | London Film School | 伦敦电影学院 |
| LFS | Looking for Squad (gaming) | 寻找小队（游戏） |
| LFS | Logistics Fleet Support | 后勤车队支持 |
| LFS | Lead Free Slug (small caliber ammunition) | 无铅弹头（小口径弹药） |
| LFS | Landing Force Support Ship | 登陆部队支援舰 |
| LFS | Loral Federal Systems | 洛拉尔联邦系统 |
| LFS | League of Filipino Students | 菲律宾学生联盟 |
| LFS | Loopback File System | 环回文件系统 |
| LFS | Legion of Fallen Souls (gaming clan) | 堕落灵魂军团（游戏氏族） |
| LFS | Low Flammability, Low Sensitivity | 低可燃性，低灵敏度 |
| LFS | Large File System | 大型文件系统 |
| LFS | Log-Structured File System (Unix, BSD) | 日志结构化文件系统（Unix、BSD） |