| DPE | Distributed Processing Environment | 分布式处理环境 |
| DPE | Double Piston Effect | 双活塞效应 |
| DPE | Developing, Printing, Enlarging | 开发、印刷、扩大 |
| DPE | Digital Parametric Equalizer (electronic signal processing) | 数字参数均衡器（电子信号处理） |
| DPE | Dangerous Pile or Embankment (ground condition) | 危险桩或路堤（地面条件） |
| DPE | Delivery Project Executive | 交付项目主管 |
| DPE | Developer and Platform Evangelist (Microsoft) | 开发人员和平台宣传员（Microsoft） |
| DPE | Department of Public Enterprises (India) | 公共企业部（印度） |
| DPE | Dieppe, France | 法国迪耶普 |
| DPE | Dye Penetrant Examination | 染料渗透检测 |
| DPE | Data Processing Engineer | 数据处理工程师 |
| DPE | dipivalyl epinephrine,dipivefrine | 二丙戊酸肾上腺素 |
| DPE | Department of Physical Education (formerly Office of Physical Education; US Military Academy) | 体育部（原美国军事学院体育办公室） |
| DPE | dipropyl ether | 二丙醚 |
| DPE | daily protein excretion | 每日蛋白质排泄 |
| DPE | death personification exercise | 死亡拟人化练习 |
| DPE | Direct Poverty Expenditure | 直接贫困支出 |
| DPE | Dynamic Project Evaluation | 动态项目评估 |
| DPE | Dipivefrin (anti-glaucoma medicine) | Dipivefrin（抗青光眼药物） |
| DPE | Designated Plan Examiner | 指定计划审查员 |
| DPE | Device Provisioning Engine | 设备配置引擎 |
| DPE | Diagnostic/Prescriptive/Evaluative | 诊断或说明性的/评价性 |
| DPE | Digital Preservation Europe | 欧洲数字保护 |
| DPE | Default Password Enumeration | 默认密码枚举 |
| DPE | Defensive Planning and Execution | 防御计划和执行 |
| DPE | Designated Pilot Examiner (conducts FAA checkrides) | 指定飞行员考官（进行FAA检查） |
| DPE | Decoupled Parameter Estimation | 解耦参数估计 |
| DPE | Demilitarization Protective Ensemble | 非军事化防护总体系统 |
| DPE | Document Processing Environment | 文档处理环境 |
| DPE | Disk Processor Enclosure | 磁盘处理器存储模块 |
| DPE | Dual-Phase Extraction (DNAPL removal system) | 双相萃取（DNAPL去除系统） |
| DPE | Diffractive Phase Element | 衍射相位元件 |
| DPE | Dihydroxyphenylethanol | 二羟基苯乙醇 |
| DPE | Data Processing Equipment | 数据处理设备 |
| DPE | Doctor of Physical Education | 体育博士 |
| DPE | Department of Postsecondary Education | 中学后教育部 |
| DPE | DELMIA Process Engineer | 工艺工程 |
| DPE | Digital Policy Environment | 数字政策环境 |