| HSSC | Home Savings Bank of Siler City (delisted) | 西勒市家庭储蓄银行（退市） |
| HSSC | Hawaii State Student Council | 夏威夷州学生委员会 |
| HSSC | Higher Secondary School Certificate | 高等中学证书 |
| HSSC | High School Summer College (Stanford University) | 高中暑期学院（斯坦福大学） |
| HSSC | Harmonised System of Survey and Certification | 检验和认证协调制度 |
| HSSC | Harris-Stowe State College (St.Louis, MO) | 哈里斯斯托州立学院（密苏里州圣路易斯） |
| HSSC | High Street Supply Chain | 高街供应链 |
| HSSC | High Speed Subcarrier Committee (National Radio Systems Committee) | 高速副载波委员会（国家无线电系统委员会） |