| SAPE | Substance Abuse Prevention And Education | 药物滥用预防和教育 |
| SAPE | Sexual Assault Peer Education | 性侵同伴教育 |
| SAPE | Students Against Practically Everything | 学生反对一切 |
| SAPE | Sexual Assault Prevention and Education | 性侵犯的预防和教育 |
| SAPE | Sapient Corp (stock symbol) | Sapient公司（股票符号） |
| SAPE | Survivable Adaptive Planning Experiment | 可生存自适应规划实验 |
| SAPE | Substance Abuse Prevention Education | 预防药物滥用教育 |
| SAPE | Sapient Corporation | Sapient公司 |