| SPDE | Solar Plasma Diagnostic Experiment | 太阳等离子体诊断实验 |
| SPDE | Speedus Corporation | Speedus公司 |
| SPDE | Solid Phase Dynamic Extraction | 固相动态萃取 |
| SPDE | stochastic partial differential equation | 随机偏微分方程 |
| SPDE | Spedus Corp (stock symbol; New York, NY) | Spedus公司（股票代码：纽约州纽约市） |
| SPDE | Service Provider Delivery Environment | 服务提供商交付环境 |