| LSU | Lithuania State University | 立陶宛国立大学 |
| LSU | Listen, Say, and Use | 听、说、用 |
| LSU | Long Sukang, Sarawak, Malaysia | 马来西亚沙捞越Long Sukang |
| LSU | Latino Student Union | 拉丁裔学生会 |
| LSU | List Super Users | 列出超级用户 |
| LSU | Love Shaq University | 爱沙克大学 |
| LSU | Labor Service Unit | 普通劳工勤务小队 |
| LSU | lactose-saccharose-urea(agar culture medium) | 乳糖-蔗糖-尿素（琼脂培养基） |
| LSU | Leyte State University | 菲律宾勒特州立大学 |
| LSU | Link State Update | 链接状态更新 |
| LSU | Landing Ship Utility | 登陆舰公用设施 |
| LSU | Laser Scanning Unit | 激光扫描单元 |
| LSU | Learning Support Unit | 学习支持股 |
| LSU | Large Subunit | 大型子单元 |
| LSU | Launcher Selector Unit | 发射器选择装置 |
| LSU | Leyte State University (formerly Visayas State College of Agriculture) | 莱特州立大学（原米沙鄢州立农业学院） |
| LSU | La Sierra University | 拉塞拉大学 |
| LSU | Link State Update (OSPF) | 链路状态更新（OSPF） |
| LSU | Loran Support Unit (USCG) | 罗兰支援部队（USCG） |
| LSU | Life Support Unit | 生命支持单元 |
| LSU | Line State Unknown (Cisco) | 线路状态未知（Cisco） |
| LSU | Loughborough Students' Union (UK) | 肯学生联盟(英国) |
| LSU | Local Synchronization Utility | 本地同步实用程序 |
| LSU | Loan Status Update | 贷款状态更新 |
| LSU | Lambda Sigma Upsilon (Latino fraternity) | Lambda Sigma Upsilon（拉丁美洲兄弟会） |
| LSU | Life Savers Underground | 地下救生员 |
| LSU | Laerdal Suction Unit | Laerdal抽吸装置 |
| LSU | Louisiana State University | 路易斯安那州立大学 |
| LSU | La Salle University (Philadelphia, PA) | 拉萨尔大学（宾夕法尼亚州费城） |
| LSU | LAN Service Unit | 局域网服务单元 |