| SPEM | Semi-Spectral Primitive Equation Model | 半谱原始方程模型 |
| SPEM | Semispectral Primitive Equation Model | 半谱本原方程模型 |
| SPEM | smooth pursuit eye movement | 平滑追击眼动 |
| SPEM | Spasmolytic Expressing Metaplasia | 痉挛性表达转移 |
| SPEM | Software Process Engineering Metamodel (OMG specification) | 软件过程工程元模型（OMG规范） |