| WISE | World Information Systems Exchange | 世界情报系统交流组织 |
| WISE | World Institute of Scientology Enterprises | 世界科学企业协会 |
| WISE | World Institute for Social Enlightenment (California) | 世界社会启蒙协会（加利福尼亚） |
| WISE | Workshop on Inspection in Software Engineering | 软件工程检验研讨会 |
| WISE | Web Intelligence Search Engine (US DoD) | Web智能搜索引擎（美国国防部） |
| WISE | Web Integrated Systems Engineering | Web集成系统工程 |
| WISE | Web Information Systems Engineering | Web信息系统工程 |
| WISE | Women Into Science and Engineering | 女性进入科学与工程 |
| WISE | Workshop on Information Systems and Economics | 信息系统与经济学讲习班 |
| WISE | Wireless Signal Extraction (transportation; real-time traffic information) | 无线信号提取（运输；实时交通信息） |
| WISE | Women's Ischemia Syndrome Evaluation (Epidemiology Data Center; University of Pittsburgh) | 妇女缺血综合症评估(流行病学资料中心,匹兹堡大学) |
| WISE | World Information Service on Energy | 世界能源信息服务 |
| WISE | Women in Spinal Cord Evolution (Frederick, MD) | 脊髓进化中的女性（Frederick，MD） |
| WISE | Web-based Integrated Science Environment | 基于Web的综合科学环境 |
| WISE | Windows Interface Source Environment (Microsoft) | Windows界面源环境（Microsoft） |
| WISE | Workplace Information Systems Enhancement | 工作场所信息系统增强 |
| WISE | Walk-In Synthetic Environment | 走进合成环境 |
| WISE | World Infrastructure Security Environment | 世界基础设施安全环境 |
| WISE | Women in Science and Engineering | 科学与工程领域的女性 |
| WISE | Women In Search of Equity | 寻求公平的妇女 |
| WISE | Western Investigation & Security Enterprises, Inc. | 西方的调查和保障企业有限公司 |
| WISE | Workplace Initiatives For Safer Environments | 工作场所安全环境倡议 |
| WISE | Writing To Improve Standards Of Excellence | 提高卓越标准的写作 |
| WISE | Women Inspired To Succeed And Excel | 女性获得成功和卓越的灵感 |
| WISE | Wireless Internet Solutions Experts | 无线互联网解决方案专家 |
| WISE | Westerns Initiative For Scholarly Excellence | 西方卓越学术倡议 |
| WISE | Wise Independent Senior Experiment | 明智的独立高级实验 |
| WISE | Wise Individualized Senior Experience | 明智的个性化高级体验 |
| WISE | Wilderness Immersion For Self Esteem | 荒野沉浸式自尊 |
| WISE | Wireless Infrastructure Simulation Environment | 无线基础设施仿真环境 |
| WISE | Wisdom Integrity Sensitivity And Enthusiasm | 智慧、正直、敏感和热情 |
| WISE | Walk In Synthetic Environment | 走进合成环境 |
| WISE | Web Interface Of Search Engine | 搜索引擎的Web界面 |
| WISE | TV-33, Fort Wayne, Indiana (formerly WKJG) | TV-33，印第安纳州韦恩堡（原WKJG） |
| WISE | Wisdom Integrity Spirituality Evangelism | 智慧正直灵性福音派 |
| WISE | Winter Semester | 冬季学期 |
| WISE | Washington Internships for Students of Engineering | 华盛顿工程学生实习 |
| WISE | Wing In Surface Effect | 翼内表面效应 |
| WISE | Write Improved SOWs Easily (manual) | 轻松编写改进的SOW（手动） |
| WISE | Wholesale Interservice Support Agreement | 批发服务间支持协议 |
| WISE | Windows of Information for Student Education (North Carolina) | 学生教育信息窗口（北卡罗来纳州） |
| WISE | Wireless System Engineering | 无线系统工程 |
| WISE | Welsh Irish Scots English | 威尔士爱尔兰苏格兰英语 |
| WISE | Workers in the Sex Industry (CBO, Act, Australia) | 性产业工人（CBO，法案，澳大利亚） |
| WISE | Work Initiatives Leading to Sustainable Employment (UK) | 促进可持续就业的工作计划（英国） |
| WISE | World And Islam Studies Enterprises | 世界与伊斯兰研究企业 |
| WISE | Workstation Interface Software Engineering (CDI) | 工作站接口软件工程（CDI） |
| WISE | Write Improved SOWs Easily | 轻松编写改进的SOW |
| WISE | Wilberforce Institute for the study of Slavery and Emancipation (UK) | 威尔伯福斯奴隶制和解放研究所（英国） |
| WISE | Words Instructions And Spelling Enrichments | 单词说明和拼写丰富 |
| WISE | World and Islam Studies Enterprise | 世界与伊斯兰研究企业 |
| WISE | Wide-Field Infrared Survey Explorer | 宽视野红外勘测探测器 |
| WISE | Welsh Initiative For Supported Employment | 威尔士支持就业倡议 |
| WISE | Women In Search Of Excellence | 追求卓越的女性 |