| COI | COordinating Investigator | 协调研究者 |
| COI | Central Office of Information | （英国）中央新闻署 |
| COI | Central Office Interface | 中心局接口 |
| COI | Composite Optics Inc. | 复合光学公司。 |
| COI | Circle of Influence (marketing) | 影响力圈（营销） |
| COI | Coefficient of Inbreeding | 近交系数 |
| COI | Conflict Of Interest | 利益冲突 |
| COI | Communications Operating Instructions | 通信操作说明 |
| COI | Committee on Infrastructure (India) | 基础设施委员会（印度） |
| COI | Cost of Insurance | 保险费用 |
| COI | Constituents of Interest | 利益构成 |
| COI | Commission OcÉanographique Intergouvernementale (French: Intergovernmental Oceanographic Commission; UNESCO) | Commission OcÉanographique Intergouvernementale (French: Intergovernmental Oceanographic Commission; UNESCO) |
| COI | Curriculum of Instruction | 教学大纲 |
| COI | Certificate of Inspection | 检验证书 |
| COI | Course Of Instruction | 教学大纲 |
| COI | Causes of Infection | 感染原因 |
| COI | Court of Inquiry | 调查法庭 |
| COI | Critical Operations Issues | 关键运营问题 |
| COI | Cost of Illness | 疾病成本 |
| COI | Community Of Interest | 利益共同体 |
| COI | ComitÉ Olimpico Internacional (Spanish: International Olympic Committee) | ComitÉ Olimpico Internacional (Spanish: International Olympic Committee) |
| COI | Contractor Operating Instructions | 承包商操作说明 |
| COI | Centre Of Influence | 影响中心 |
| COI | City Of Industry | 工业城市 |
| COI | Commencement of Injection (auto engine) | 喷射开始（汽车发动机） |
| COI | Contact of Interest | 感兴趣的联系人 |
| COI | Current Operations and Intelligence | 当前操作和情报 |
| COI | Chief Of Implementation | 执行主任 |
| COI | Charge Ordered Insulating | 电荷有序绝缘 |
| COI | Church Of Iron | 铁之教堂 |
| COI | Commission de l'OcÉan Indien | Commission de l'OcÉan Indien |
| COI | Communications Operating Instruction | 通信操作说明 |
| COI | Critical Operational Issue | 紧急通信作业问题 |
| COI | coenzyme I | 辅酶I |
| COI | Center Of Influence | 影响中心 |
| COI | Certificate Of Insurance (insurance) | 保险证明书（保险） |
| COI | Certificate Of Identicality | 身份证明 |
| COI | Coalition of Itan (gaming guild) | 伊坦联盟（游戏公会） |
| COI | Career Orientation Inventory | 职业方向清单 |
| COI | Crossroads Online Institute | 十字路口在线研究所 |
| COI | Cut-Off Index (medicine) | 截止指数（医药） |
| COI | Continuous Optical Irradiation | 连续光学照射 |
| COI | Coloboma of Iris, Choroid, and Retina | 虹膜、脉络膜和视网膜缺损 |
| COI | Community Of Immortality | 不朽社区 |
| COI | Church Of Ireland | 爱尔兰教会 |
| COI | Cytochrome Oxidase I | 细胞色素氧化酶I |
| COI | Commission de l'OcÉan Indien (Indian Ocean Commission) | Commission de l'OcÉan Indien (Indian Ocean Commission) |
| COI | Chronic Orthostatic Intolerance | 慢性矫正不耐受 |
| COI | Canadian Outcomes Institute | 加拿大成果研究所 |
| COI | Contingency Orbit Insertion | 应急轨道插入 |
| COI | Coordinator Of Information | 信息协调员 |
| COI | Cone of Influence (symbolic model checking procedure) | 影响锥（符号模型检查程序） |
| COI | Country of Origin Information | 原产国信息 |
| COI | Cause of Insanity (band) | 疯狂的原因（乐队） |
| COI | Committee on Information | 新闻委员会 |
| COI | Confirmed Opt-In (email mailing list regiatration confirmation procedure) | 已确认的选择加入（电子邮件邮件列表注册确认程序） |
| COI | Co-Investigator | 联合研究者 |
| COI | Coast Orbital Insertion (NASA) | 海岸轨道插入（NASA） |
| COI | Cogent Communications Group, Inc. | 科金特通信集团。 |
| COI | Class Of Interface | 接口类别 |
| COI | Chickens On Ice | 冰上的鸡 |
| COI | Coastal Ocean Institute (Woods Hole Oceanographic Institution) | 沿海海洋研究所（伍兹霍尔海洋研究所） |
| COI | Chief of Initiatives | 倡议负责人 |
| COI | Centers of Influence | 影响中心 |
| COI | Country of Interest | 感兴趣的国家 |
| COI | Chief of Installation | 安装负责人 |
| COI | Certified Online Instructor | 认证在线讲师 |
| COI | Circles Of Interest | 兴趣圈 |