| SAIC | State Administration for Industry and Commerce | （中国）国家工商行政管理局 |
| SAIC | Science Applications International Corporation | 科学应用国际公司 |
| SAIC | Special Agent In Charge (US Secret Service) | 主管特工（美国特勤局） |
| SAIC | Ship Acquisition & Improvement Council | 船采集和改进 |
| SAIC | Shanghai Administration of Industry and Commerce | 上海市工商行政管理局 |
| SAIC | South African Indian Congress | 南非印第安人大会 |
| SAIC | State Administration of Industry and Commerce (China) | 国家工商行政管理局（中国） |
| SAIC | School of the Art Institute of Chicago | 芝加哥艺术学院 |
| SAIC | Secondary Antenna Interface Controller (AN/FSC-78B SATCOM terminal) | 二次天线接口控制(一种/ FSC-78B卫通终端) |
| SAIC | Shanghai Automotive Industry Corp. Group (GM) | 上海汽车工业集团公司（GM） |
| SAIC | Structured Akaike Information-theoretic Criteria | 结构化Akaike信息论准则 |
| SAIC | Saint Anthony Immaculate Conception (San Francisco, CA school) | 圣安东尼无玷污受孕（加州旧金山学校） |
| SAIC | Single Antenna Interference Cancellation | 单天线干扰消除 |