| DISC | death-inducing signaling complex | 死亡诱导信号复合物 |
| DISC | DISA Information Systems Center | DISA信息系统中心 |
| DISC | Digital Interactive Sports Card | 数字互动运动卡 |
| DISC | Dynamic Information Systems Corporation | 动态信息系统公司 |
| DISC | Distributor Information Systems Corporation | 分销商信息系统公司 |
| DISC | Design Information System Center | 设计信息系统中心 |
| DISC | Development Information Services Clearinghouse (USAID) | 发展信息服务中心（USAID） |
| DISC | Decision Information System For Citrus | 柑橘决策信息系统 |
| DISC | Data and Information Services for CliC (Climate and Cryosphere) | CliC（气候和冰冻圈）数据和信息服务 |
| DISC | Discover Information Security Compliance (Discover's payment card industry data security standard compliance program) | 发现信息安全相关的行业标准支付信用卡数据安全检查程序 |
| DISC | Data Information Service Center | 数据信息服务中心 |
| DISC | Differential Scattering | 微分散射 |
| DISC | Digital International Switching Center | 数字国际交换中心 |
| DISC | Disconnect Command | 断开连接命令 |
| DISC | Developing In Service Course | 开发在职课程 |
| DISC | Dominance Influence Steadiness And Compliance | 支配地位影响稳定性和合规性 |
| DISC | Digital Information Services Center (Netherlands) | 数字信息服务中心（荷兰） |
| DISC | Demonstrators For Integrated Ship Control | 综合船舶控制演示 |
| DISC | Domain For Innovative Software Content | 创新软件内容领域 |
| DISC | Document Imaging Services Company | 文档图像服务公司 |
| DISC | Direct-Injection Stratified Charge engine | 直接喷射分层增压发动机 |
| DISC | Dental Interactive Simulations Corporation | 牙科互动模拟公司 |
| DISC | Discover (credit card) | 发现（信用卡） |
| DISC | Digital Integration Systems & Consultancy | 数字集成系统和咨询 |
| DISC | Digital Information Science And Communication | 数字信息科学与通信 |
| DISC | Drop In Study Centre | 临时学习中心 |
| DISC | Defense Information System Council | 国防信息系统委员会 |
| DISC | Data Information Systems And Communications | 数据信息系统和通信 |
| DISC | Dominance/Influence/Steadiness/Conscientiousness (personality profile) | 优势/影响/稳定/自觉(人格剖面) |
| DISC | Defense Industrial Supply Center | 国防工业品供应中心 |
| DISC | Disaster Information Systems Clearinghouse | 灾害信息系统信息交换所 |
| DISC | Domestic International Sales Corporation | 国内国际销售公司 |
| DISC | Domestic Industrial Sales Corporation | 国内工业销售公司 |
| DISC | Digital Information Service For Computerfreaks | 电脑迷的数字信息服务 |
| DISC | Distributed Computing (International Symposium) | 分布式计算（国际研讨会） |
| DISC | Directory Of International Studios And Control | 国际工作室和控制目录 |
| DISC | discover | 发现 |
| DISC | DNA Information and Stock Center | DNA信息和库存中心 |
| DISC | discontinue(d) | 中止（d） |
| DISC | Diplomatic Intelligence Support Center | 外交情报支持中心 |
| DISC | Digital Information Systems Corporation | 数字信息系统公司 |
| DISC | Data Index for Software Configuration | 软件配置数据索引 |
| DISC | Diversity Incorporating Safer Communities | 融入更安全社区的多样性 |
| DISC | Dominance, Influence, Steadiness, Conscientiousness | 统治力、影响力、稳定性、责任心 |
| DISC | Delay In Separation Code | 分离代码延迟 |
| DISC | Death-Inducing Signaling Complex (cell apoptosis) | 死亡诱导信号复合物（细胞凋亡） |
| DISC | Data and Information Service for CliC | CliC的数据和信息服务 |
| DISC | diffuse inflammatory salmon patch choroidopathy | 弥漫性炎性鲑鱼斑脉络膜病 |