| SCO | Shanghai Cooperation Organization | 上海合作组织 |
| SCO | Scotland | 苏格兰 |
| SCO | Set Time Counter | 置位时间计数器 |
| SCO | Subcarrier Oscillator | 副载波振荡器 |
| SCO | Senior Credit Officer (banking) | 高级信贷官（银行） |
| SCO | Senior Care Options | 老年护理选项 |
| SCO | Santa Cruz Operation | 圣克鲁斯运营 |
| SCO | Signals Communications Officer | 信号通信官 |
| SCO | Sharable Content Object | 可共享内容对象 |
| SCO | Southern Cycling Operations | 南方自行车运营 |
| SCO | Single-Cell Optimum | 单电池最佳 |
| SCO | SociÉtÉ Canadienne d'Ophthalmologie (Canadian Ophthalmological Society) | SociÉtÉ Canadienne d'Ophthalmologie (Canadian Ophthalmological Society) |
| SCO | Surface Contaminated Object | 表面污染物体 |
| SCO | Summary Court Officer | 简易法庭官员 |
| SCO | Self Check Out | 自助结账 |
| SCO | Specialist Coalition of Ontario | 安大略省专家联盟 |
| SCO | State Cleanup Order | 状态清理顺序 |
| SCO | System Control Officer | 系统控制官 |
| SCO | Social Compliance Officer (human resources) | 社会合规官（人力资源） |
| SCO | Safety Condition for Operation | 操作安全条件 |
| SCO | Santa Cruz Operations | 圣克鲁斯运营 |
| SCO | Senior Commercial Officer | 高级商务官 |
| SCO | Slimy Crude Operations | 稠油作业 |
| SCO | Special Company Order | 特殊公司订单 |
| SCO | Sun Collaborative Opportunity | Sun协作机会 |
| SCO | Score - best results | 得分-最佳结果 |
| SCO | Special Communication Organization | 特殊通信组织 |
| SCO | Soft Copy Only | 仅软拷贝 |
| SCO | Skin Care Options | 皮肤护理选项 |
| SCO | Safety Code Officer | 安全规范员 |
| SCO | Selective Contingency Options | 选择性应急选项 |
| SCO | Senior Civilian Official | 高级文职官员 |
| SCO | Systems Control Officer | 系统控制官 |
| SCO | structure-conduct-outcomes | 结构行为结果 |
| SCO | System/Secondary Control Officer | 系统/中等管理部门的官员 |
| SCO | Self-Consistent Orbital | 自洽轨道 |
| SCO | Synthetic Crude Oil | 合成原油 |
| SCO | Show Cause Order (legal summons) | 出示原因令（法律传票） |
| SCO | State Coordinating Officer (FEMA) | 州协调官员（FEMA） |
| SCO | Senior Court Officer | 高级法院官员 |
| SCO | Scots | 苏格兰人 |
| SCO | Squadron Commander | 中队指挥官 |
| SCO | Synchronous Connection Oriented | 面向同步连接 |
| SCO | Single Crossing Over | 单渡线 |
| SCO | Shell of a Computer Organization | 计算机组织的外壳 |
| SCO | Scor S. A. | 得分S.A。 |
| SCO | Aktau, Kazakstan | 哈萨克斯坦阿克套 |
| SCO | Super Charged Oxygen | 超级充电氧气 |
| SCO | Seasonal Climate Outlook | 季节性气候展望 |
| SCO | Space Control Officer | 空间管制干事 |
| SCO | Supreme Court of Ontario | 安大略省最高法院 |
| SCO | Shipboard-Controlled Intercept | 舰载控制拦截 |
| SCO | Sales Contracting Officer | 销售合同官员 |
| SCO | Sporting Club de l'Ouest (Angers, France soccer club) | 体育俱乐部'Ouest de fixation(激怒,法国足球俱乐部) |
| SCO | Soft Corporate Offer | 公司软报价 |
| SCO | Synchronous Connection-Oriented Link (Bluetooth) | 面向连接的同步链路（蓝牙） |
| SCO | Service Certifying Organization | 服务认证机构 |
| SCO | Statistical Control Office | 统计控制办公室 |
| SCO | Supply Chain Optimization | 供应链优化 |
| SCO | Secondary Control Officer | 二级控制官 |
| SCO | Sertoli Cell-Only | 仅支持细胞 |
| SCO | Scope Change Operator | 范围更改运算符 |
| SCO | Scholarship Coordination Office | 奖学金协调办公室 |
| SCO | Sub-Control Office | 分控办公室 |
| SCO | Special Communication Organization (Pakistan) | 特别通讯组织（巴基斯坦） |
| SCO | Sub-Carrier Oscillator | 副载波振荡器 |
| SCO | Senior Canadian Officer (Canada) | 加拿大高级官员（加拿大） |
| SCO | Successor Contracting Officer | 继任合同官员 |