| ISSR | International Society for Science and Religion ( University of Cambridge, UK) | 国际科学与宗教协会（英国剑桥大学） |
| ISSR | Incremental Software Specification Review | 增量软件规范评审 |
| ISSR | Inter Simple Sequence Repeat (genetic identification technology) | 简单序列间重复序列（遗传鉴定技术） |
| ISSR | In School Suspension Room | 学校休学室 |
| ISSR | In-Service Support Review | 服务中支持审查 |
| ISSR | Internal Software Specification Review | 内部软件规范审查 |
| ISSR | Institute for Social Science Research | 社会科学研究所 |
| ISSR | Inside Screening Router | 内部筛选路由器 |
| ISSR | ISS Rail Incorporated | ISS铁路公司 |
| ISSR | Information Systems Security Representative | 信息系统安全代表 |
| ISSR | IBM Software Services Rational | IBM软件服务Rational |