| USB | Universal Serial Bus | 通用串行总线 |
| USB | Upper Side Band | 上边带 |
| USB | Union State Bank | 联邦国家银行 |
| USB | U S Bancorp of Delaware | 美国特拉华银行 |
| USB | US Bank | 美国银行 |
| USB | United Southern Bank (formerly Umatilla State Bank) | 联合南方银行（原Umatila State Bank） |
| USB | Ultimate Security Breakdown | 最终安全故障 |
| USB | Universal Studio Bridge | 环球影城大桥 |
| USB | Universal Style Bank | 通用样式库 |
| USB | Unusually Slow Bus | 非常慢的公共汽车 |
| USB | University of South Berkly | 南伯克利大学 |
| USB | Unstable Synthetic Brain | 不稳定合成脑 |
| USB | Ultimate Sound Bank | 终极声音库 |
| USB | Undergraduate School of Business | 本科商学院 |
| USB | Useless Steam Blowhole | 无用蒸汽气孔 |
| USB | User Sensitive Billing | 用户敏感计费 |
| USB | Upper Sideband | 上边带 |
| USB | Unteres Seitenband (German: lower sideband) | Unteres Seitenband（德语：下边带） |
| USB | Universidad Simon Bolivar (Venezuela) | 西蒙玻利瓦尔大学（委内瑞拉） |
| USB | Uniwersytet Stefana Batorego (Polish: Stephen Batory University; former Polish name of Vilnius University) | Uniwersytet Stefana Batorego（波兰语：Stephen Batory University；维尔纽斯大学的前波兰语名称） |
| USB | Urban Service Boundary | 城市服务边界 |
| USB | University At Stonybrook (SUNY) | Stonybrook大学（SUNY） |
| USB | Unified S-Band (satellite technology) | 统一S波段（卫星技术） |
| USB | Usage Sensitive Billing | 使用敏感计费 |
| USB | United Soybean Board | 联合大豆委员会 |
| USB | Unsporting Behaviour (soccer) | 不良行为（足球） |
| USB | Unicode Subset Bitfield | Unicode子集位字段 |
| USB | Upflow Sludge Bed | 上流式污泥床 |
| USB | University Star Building | 大学之星大厦 |
| USB | User's Support Branch | 用户的支持分支 |
| USB | Ultrasound-Guided Aspiration Biopsy | 超声引导抽吸活检 |