| DME | dimethoxyethane | 二甲醚 |
| DME | Distance Mesurement Equipment | 测距设备 |
| DME | Direct Memory Execute | 直接内存执行 |
| DME | Digital Motor Electronics | 数字式引擎控制电脑 |
| DME | Drug-metabolizing enzyme | 药物代谢酶 |
| DME | Digital Multiplex Equipment | 数字复用设备 |
| DME | Distributed Management Environment | 分布式管理环境 |
| DME | Digital Multiple Effect | 数字多功能特技 |
| DME | Data Medium Exchange (SAP interface, bank transfers) | 数据介质交换（SAP接口、银行转账） |
| DME | Moscow, Russia - Domodedovo (Airport Code) | 俄罗斯莫斯科-多莫杰多沃（机场代码） |
| DME | Designated Medical Examiner (US FAA) | 指定医学检查员（美国联邦航空局） |
| DME | Direct Micro Expelling | 直接微量排出 |
| DME | Diploma in Mechanical Engineering | 机械工程大专文凭 |
| DME | Durable Medical Equipment | 耐用医疗设备 |
| DME | Digital Mafia Enterprises, LLC | 数字黑手党企业有限责任公司 |
| DME | Dakota Minnesota and Eastern Railroad Corporation | 达科他州明尼苏达州和东部铁路公司 |
| DME | Divine Materialize Energy | 神圣物质化能量 |
| DME | Development, Modernization, and Enhancement | 发展、现代化和增强 |
| DME | Dubai Mercantile Exchange Limited | 迪拜商品交易所有限公司 |
| DME | Data Modulation Encoder | 数据调制编码器 |
| DME | Dubai Mercantile Exchange | 迪拜商品交易所 |
| DME | Decision Making Exercise | 决策训练 |
| DME | Direct Marketing Expense | 直接营销费用 |
| DME | Direct Measurement Explorer | 直接测量浏览器 |
| DME | Dry Malt Extract | 干麦芽提取物 |
| DME | 1,2-dimethoxyethylene | 1,2-二甲氧基乙烯 |
| DME | Domestic Marijuana Eradication Program | 国内大麻根除计划 |
| DME | dimethyoxyethane | 二甲氧基乙烷 |
| DME | diphasic meningoencephalitis | 双相脑膜脑炎 |
| DME | Domodedovo, Russia | 俄罗斯多莫杰多沃 |
| DME | Dielectric Midgap Energy Model | 介质中隙能量模型 |
| DME | Dmapedit (gaming map editor) | Dmapedit（游戏地图编辑器） |
| DME | Digital Motor Electronic | 数字电机电子 |
| DME | Dell Media Experience | Dell媒体体验 |
| DME | Dime Bancorp, Inc. | Dime Bancorp公司。 |
| DME | Diastatic Malt Extract | Diastatic麦芽提取物 |
| DME | Department of Medical Education (Armed Forces Institute of Pathology) | 医学教育部（武装部队病理研究所） |
| DME | Dried Malt Extract | 干麦芽提取物 |
| DME | Direct Machine Environment | 直接机器环境 |
| DME | Dropping Mercury Electrode | 滴汞电极 |
| DME | Distance Measuring Equipment | 距离测量设备 |
| DME | Diabetic Macular Edema | 糖尿病黄斑水肿 |
| DME | Deputy Medical Examiner | 副体检员 |
| DME | Design Margin Evaluation | 设计裕度评估 |
| DME | Dynamic Modulus of Elasticity | 动态弹性模量 |
| DME | Diatomaceous Earth | 硅藻土 |
| DME | Direct Manufacturing Expense | 直接制造费用 |
| DME | Direction-Biased Motion Estimation | 方向偏置运动估计 |
| DME | Digital Media Exchange, Inc. (Philippines) | 数字媒体交换公司（菲律宾） |
| DME | Deputy Managing Editor | 副总编辑 |
| DME | Dimethylether | 二甲醚 |
| DME | Dialogue, Music & Effects (from audio post-production, a type of deliverable mix) | 对话,音乐及效果(从音频后期制作,一种可组合) |
| DME | Design Mission Effect | 预计任务的效果 |
| DME | Digital Media Edition (Microsoft) | 数字媒体版（Microsoft） |
| DME | Dynamic Mid-range Exchange | 动态中端交换 |
| DME | Department of Minerals and Energy | 矿产和能源部 |
| DME | Drive Motor Electronics | 驱动电机电子 |
| DME | Doctorate of Music Education | 音乐教育博士 |
| DME | Dakota Minnesota & Eastern (railroad) | 达科塔明尼苏达州和东部(铁路) |