| SPADE | Society for Promotion of Appropriate Development Efforts (India) | 促进适当发展努力协会（印度） |
| SPADE | Simulated Penetrated Air Defense Exercise | 模拟突防演习 |
| SPADE | Spatialization and Auditory Display Environment (Ireland) | 空间化和听觉展示环境（爱尔兰） |
| SPADE | Single channel per carrier PCM multiple Access Demand assignment Equipment (ITU-T) | 每载波单信道PCM多址需求分配设备（ITU-T） |
| SPADE | Small Portable Analyzer Diagnostic Equipment | 小型便携式分析仪诊断设备 |
| SPADE | Sparta Acquisition Digital Equipment | 斯巴达采集数字设备 |
| SPADE | Solar and Polaris Azimuth Determination | 太阳和北极星方位角测定 |
| SPADE | Spare Parts Analysis, Documentation & Evaluation | 零部件分析、文件及评估 |
| SPADE | Stratospheric Photochemistry, Aerosols and Dynamics Expedition (NASA aircraft campaign, Ames Research Center, California | 平流层光化学、气溶胶和动力学远征（NASA飞机活动，加利福尼亚州埃姆斯研究中心 |
| SPADE | Signal Processor and Display Equipment | 信号处理器和显示设备 |
| SPADE | Statistical Packet Anomaly Detection Engine | 统计数据包异常检测引擎 |
| SPADE | Software Process Analysis Design And Enactment | 软件过程分析设计与实施 |
| SPADE | Settable Pneumatic Altitude Detection | 可设置气动高度检测 |
| SPADE | Stratospheric Photochemistry, Aerosols, and Dynamics Expedition | 平流层光化学、气溶胶和动力学考察 |