| ISSS | Initial Sector Suite Subsystem | 起始扇区管制席位分系统 |
| ISSS | Interactive Subscriber Service Subsystem | 交互式服务子系统 |
| ISSS | Information Society Standardization System | 信息社会标准化体系 |
| ISSS | International Student and Scholar Services | 国际学生和学者服务 |
| ISSS | Initial Sector Suite System | 初始扇区套件系统 |
| ISSS | Information Systems Security Standards | 信息系统安全标准 |
| ISSS | Inherent Secondary Shutdown System | 固有二次停车系统 |
| ISSS | International Services for Students & Scholars | 为学生和学者的国际服务 |
| ISSS | International Soil Science Society (Italy) | 国际土壤科学学会（意大利） |
| ISSS | International Society for Seed Science (Vermillion, South Dakota) | 国际种子科学学会（南达科他州维密） |
| ISSS | International Society for the Systems Sciences | 国际系统科学学会 |
| ISSS | International Symposium on Skill Science | 技能科学国际研讨会 |
| ISSS | IMASE Simulation and Scoring Subsystem | IMASE模拟和评分子系统 |
| ISSS | Installation Service Supply Support | 设施勤务供应支援 |
| ISSS | International Symposium on Systems Synthesis | 系统综合国际研讨会 |
| ISSS | Instituto da Solidariedade e Segurança Social (Portugal) | Instituto da Solidariedade e Segurança Social (Portugal) |
| ISSS | Integrated Spatial Information Systems | 综合空间信息系统 |
| ISSS | International Society of Soil Science | 国际土壤学会 |
| ISSS | Interim Strategic Storage Site | 临时战略存储站点 |
| ISSS | Internet Self Service and Security (Sprint) | 互联网自助服务和安全（Sprint） |