| SOFIA | Society of Film Archivists | 电影档案工作者协会 |
| SOFIA | State of World Fisheries and Aquaculture | 世界渔业和水产养殖状况 |
| SOFIA | South Florida Information Access | 南佛罗里达州信息访问 |
| SOFIA | Stratospheric Observatory for Infrared Astronomy | 红外天文平流层天文台 |
| SOFIA | Support Our Friends in Iraq and Afghanistan | 支持我们在伊拉克和阿富汗的朋友 |
| SOFIA | SociÉtÉ Française des Infirmier(e)s AnesthÉsistes (French society of nurses anesthetists) | SociÉtÉ Française des Infirmier(e)s AnesthÉsistes (French society of nurses anesthetists) |