| RDE | Merdey, Indonesia | 印度尼西亚默迪 |
| RDE | Rectal Digital Examination | 直肠数字化检查 |
| RDE | Remote Data Entry | 远程数据输入 |
| RDE | Remote Data Engagement | 远程数据参与 |
| RDE | Right Defensive End (pro football) | 右防守端（职业足球） |
| RDE | Route Determination Entity | 路线确定实体 |
| RDE | Received Data Enable | 接收数据启用 |
| RDE | Rotating Disk Electrode | 旋转圆盘电极 |
| RDE | Rapid Development Environment | 快速发展环境 |
| RDE | Responsible Design Engineer | 责任设计工程师 |
| RDE | Robust Design Engineering | 稳健设计工程 |
| RDE | Rapidly Developing Economy | 快速发展的经济 |
| RDE | RASSP Design Environment | RASP设计环境 |
| RDE | Registered Dietitian Eligible | 合格注册营养师 |
| RDE | Requirements Data Exchange | 需求数据交换 |
| RDE | Rule Developing Experimentation (from the book Selling Blue Elephants) | 规则制定实验（摘自《卖蓝大象》一书） |
| RDE | Research Development and Extension | 研究开发和扩展 |
| RDE | Reaction Diffusion Equation | 反应扩散方程 |
| RDE | Riccati Differential Equation | Riccati微分方程 |
| RDE | Reuse-Driven Development Environment | 重用驱动的开发环境 |
| RDE | receptor destroying enzyme | 受体破坏酶 |
| RDE | Research, Development, and Engineering | 研究、开发和工程 |