| OPO | Porto, Portugal - Porto (Airport Code) | 波尔图，葡萄牙-波尔图（机场代码） |
| OPO | Owen, Patterson, & Owen | 欧文•派和欧文 |
| OPO | Porto, Portugal | 葡萄牙波尔图 |
| OPO | Object file (Psion OPL) | 对象文件（Psion OPL） |
| OPO | Operational Performance Objective | 运营绩效目标 |
| OPO | Old Post Office | 旧邮局 |
| OPO | Office Products Outlet | 办公产品网点 |
| OPO | Order Pizza for Operator | 为操作员订购披萨 |
| OPO | Optical Parametric Oscillator | 光学参量振荡器 |
| OPO | onchocercal punctate opacity | 盘尾丝虫点状混浊 |
| OPO | Opposite Polarity | 相反极性 |
| OPO | Office of Personnel Operations | 人事运营办公室 |
| OPO | Psion OPL Output (executable file extension) | Psion OPL输出（可执行文件扩展名） |
| OPO | Ohio Peace Officer | 俄亥俄州和平官员 |
| OPO | One Person Operated | 一人操作 |
| OPO | Organ Procurement Organization | 器官采购组织 |
| OPO | Optical Parametric Oscillator(s) | 光学参量振荡器 |
| OPO | Orbiter Project Office | 轨道飞行器计划处 |
| OPO | Office of Public Outreach (NASA) | 公共外联办公室（NASA） |
| OPO | Outpatient Observation | 门诊观察 |
| OPO | Orbiting Planetary Observatory | 轨道行星天文台 |
| OPO | Oil Pressure Out | 机油压力输出 |
| OPO | Ovamboland People's Organization | Ovamboland人民的组织 |
| OPO | One Production Only (acting contracts) | 仅一次生产（代理合同） |
| OPO | OPNAV Principal Official | OPNAV主要官员 |
| OPO | Operational Performance Objectives | 运营绩效目标 |
| OPO | Over-Pressure Operations | 超压操作 |
| OPO | Office of Provincial Outreach | 省外联办公室 |