| ISOC | Internet SOCiety | Internet协会 |
| ISOC | Islamic Society of Orange County | 奥兰治县伊斯兰协会 |
| ISOC | Internation Society Of Cultures | 国际文化协会 |
| ISOC | in situ Submerged Oxygen Curtain (trademark of inVentures Technologies, Inc.) | 原位浸没式氧气幕（inVentures Technologies，Inc.的商标） |
| ISOC | IP Security Operations Center | IP安全运营中心 |
| ISOC | Internal Security Operations Command (Thailand) | 内部安全行动司令部（泰国） |
| ISOC | In-Service Open Challenge (Disney lifeguard competition) | 在职公开挑战赛（迪斯尼救生员比赛） |