| DESA | Destroyer Escort Sailors Association | 驱逐舰护航水手协会 |
| DESA | Diabetes Exercise & Sports Association | 糖尿病运动和运动协会 |
| DESA | Defence Explosives Safety Authority (United Kingdom) | 国防爆炸物安全管理局（联合王国） |
| DESA | Defense Evaluation Support Activity | 国防评估支持活动 |
| DESA | Department of Economic and Social Affairs | 经济和社会事务部 |
| DESA | District Explorer Scout Administrator (UK scouting) | 地区探险家童军管理员（英国童军） |
| DESA | Defense Evaluation Support Agency | 国防评估支持机构 |
| DESA | Diplomate of the European Society of Anaesthesiology | 欧洲麻醉学会文凭 |