| LSE | London School of Economics and Political-Science | 伦敦大学经济政治学系 |
| LSE | London School of Economics | 伦敦经济学院 |
| LSE | London Stock Exchange | 伦敦证券交易所 |
| LSE | Layer Service Element | 层服务单元 |
| LSE | Line Signaling Equipment | 线路信令设备 |
| LSE | Link Switch Equipment | 链路交换设备 |
| LSE | Local System Environment | 本地系统环境 |
| LSE | La Crosse, WI, USA - La Crosse Municipal (Airport Code) | 美国威斯康星州拉克罗斯-拉克罗斯市政（机场代码） |
| LSE | London School of Economics & Political Science (UK) | 伦敦学派的经济学和政治学(英国) |
| LSE | Live Sheep Export | 活羊出口 |
| LSE | Lease (classifieds) | 租赁（分类广告） |
| LSE | Least Side-Lobe Energy | 最小旁瓣能量 |
| LSE | Leadership Self-Efficacy (management) | 领导自我效能（管理） |
| LSE | Logistics Support Element | 后勤保障要素 |
| LSE | Large Scale Enterprise | 大型企业 |
| LSE | Loose | 释放 |
| LSE | London School of English (London, England, UK) | 伦敦英语学校（英国伦敦） |
| LSE | Logistics Support Equipment | 后勤保障设备 |
| LSE | Land Surface Experiment | 陆地表面实验 |
| LSE | Life-Skills Education | 生活技能教育 |
| LSE | Language Sensitive Editor | 语言敏感编辑器 |
| LSE | Luxury Super Express | 豪华超级快车 |
| LSE | Local Security Environment | 当地安全环境 |
| LSE | La Crosse, Wisconsin USA | 美国威斯康辛州拉克罗斯 |
| LSE | Low Surface Energy | 低表面能 |
| LSE | Lead System Engineer | 首席系统工程师 |
| LSE | Life Skills Education (UNICEF) | 生活技能教育（联合国儿童基金会） |
| LSE | Longitudinal Section Electric (mode) | 纵断面电动（模式） |
| LSE | Load-Serving Entity | 加载服务实体 |
| LSE | Lahore Stock Exchange (Pakistan) | 拉合尔证券交易所（巴基斯坦） |
| LSE | Low Self-Esteem | 自卑 |
| LSE | Laboratory Support Equipment | 实验室支持设备 |
| LSE | Least Squares Estimate | 最小二乘估计 |
| LSE | Life Style Extra (UK) | Life Style Extra（英国） |
| LSE | Left Sternal Edge (auscultation of heart sounds) | 左胸骨边缘（心音听诊） |
| LSE | Lahore Stock Exchange | 拉合尔证券交易所 |
| LSE | Life Support Equipment | 生命支持设备 |
| LSE | Local Subscriber Environment | 本地订户环境 |
| LSE | Latex Sphere Equivalent | 乳胶球当量 |
| LSE | Limite SupÉrieure d'ExplosibilitÉ (French: Upper Flammable Limit) | Limite SupÉrieure d'ExplosibilitÉ (French: Upper Flammable Limit) |
| LSE | Living Skin Equivalent | 活体皮肤当量 |
| LSE | Landing Signal Enlisted | 登陆信号兵 |
| LSE | Lincoln Southeast High School (Lincoln, Nebraska) | 林肯东南高中（内布拉斯加州林肯） |
| LSE | Log-Spectral-Error | 对数谱误差 |