| SEF | Strait Exchange Foundation (of Taiwan, China) | 海峡交流基金会(海基会) |
| SEF | Southern Education Foundation | 南方教育基金会 |
| SEF | Small Enterprise Foundation | 小型企业基金会 |
| SEF | Serviço de Estrangeiros e Fronteiras (Portugal; Portuguese Immigration and Border Control Office) | Serviço de Estrangeiros e Fronteiras (Portugal; Portuguese Immigration and Border Control Office) |
| SEF | Smaps Exchange Format | Smaps交换格式 |
| SEF | Systeme d'Encheres (French: Bridge card game bidding system) | 'Encheres Systeme d(法国:桥纸牌游戏招投标制度) |
| SEF | Spectral Energy Flux | 光谱能量通量 |
| SEF | School Evaluation Framework (UK) | 学校评估框架（英国） |
| SEF | Sebring, Florida USA | 美国佛罗里达州塞布林 |
| SEF | somatically evoked field | 躯体诱发场 |
| SEF | sodium excreting factor | 钠排泄因子 |
| SEF | Self Evaluation Formula | 自我评估公式 |
| SEF | staphylococcal enterotoxin f | 葡萄球菌肠毒素f |
| SEF | Special Elite Forces (gaming clan) | 特种精英部队（游戏部落） |
| SEF | Single Ended Fast | 单端快速 |
| SEF | Straits Exchange Foundation (China) | 海峡交流基金会（中国） |
| SEF | Stonington Education Fund | 斯托宁顿教育基金 |
| SEF | Secure Enclave Firewall | 安全Enclave防火墙 |
| SEF | Simplified Edi Format | 简化的Edi格式 |
| SEF | Sustaining Engineering Facility | 持续工程设施 |
| SEF | Sensitive Earth Fault | 敏感接地故障 |
| SEF | Search Engine Friendly | 搜索引擎友好 |
| SEF | Sustainable Energy Fund (Pennsylvania) | 可持续能源基金（宾夕法尼亚州） |
| SEF | Spectral Edge Frequency | 光谱边缘频率 |
| SEF | Short Edge First (printer paper handling) | 短边优先（打印机纸张处理） |
| SEF | Software Engineering Facility | 软件工程设施 |
| SEF | sealift enhancement feature (US DoD) | 海运增强功能（美国国防部） |
| SEF | Source Explicit Forwarding | 源显式转发 |
| SEF | Sankara Eye Foundation | 桑卡拉眼科基金会 |
| SEF | Sex Education Forum | 性教育论坛 |
| SEF | Symantec Enterprise Firewall | 赛门铁克企业防火墙 |
| SEF | SPECAT Exclusive For | SPECAT专用 |
| SEF | Shape Error Forecasting | 形状误差预测 |
| SEF | Sociedad Española de FitopatologÍa (Spanish: Spanish Society of Phtyopathology) | Sociedad Española de FitopatologÍa (Spanish: Spanish Society of Phtyopathology) |
| SEF | Self Extinguishing Fabric (Modacrylic) | 自熄织物（Modacrylic） |
| SEF | Severely Errored Frame | 严重错误的帧 |
| SEF | Sign Each Frame | 为每一帧签名 |
| SEF | Software Enhancement Form | 软件增强表单 |