| HSS | High Speed Switch | 高速交换机 |
| HSS | High-Speed Steel | 高速钢 |
| HSS | Hrvatski Softball Savez (Croatian Softball Association) | Hrvatski垒球Savez（克罗地亚垒球协会） |
| HSS | Humanities and Social Sciences | 人文社会科学 |
| HSS | Hot Spot Simulators | 热点模拟器 |
| HSS | Hunter Sensor Suite | 亨特传感组合 |
| HSS | Hughes Software Systems (subsidiary of Hughes Network Systems) | 休斯软件系统公司（休斯网络系统公司的子公司） |
| HSS | Hallermann-Streiff Syndrome | Hallermann-Streiff综合征 |
| HSS | Heat Shrink Sleeve (coating industry) | 热缩套管（涂料行业） |
| HSS | History of Science Society | 科学社会史 |
| HSS | High Speed Sealift | 高速海运 |
| HSS | Hydraulic Steel Structures (USACE) | 水工钢结构（USACE） |
| HSS | Hulu Sungai Selatan | Hulu Sungai Selatan公司 |
| HSS | Hospital for Special Surgery (New York, NY, USA) | 特殊外科医院（美国纽约州纽约市） |
| HSS | Host System Software (ITI) | 主机系统软件（ITI） |
| HSS | Health Support Service (Australia) | 健康支持服务（澳大利亚） |
| HSS | Hypothetical Stream Scheduler (digital TV) | 虚拟流调度程序（数字电视） |
| HSS | Haemonetics Software Solutions (Edmonton, Alberta, Canada) | Haemonetics软件解决方案（加拿大阿尔伯塔省埃德蒙顿） |
| HSS | High Speed Steel | 高速钢 |
| HSS | Hallervorden-Spatz Syndrome | Hallervorden-Spatz综合征 |
| HSS | Health Service Support | 医务支援 |
| HSS | Hunter Sensor System | 亨特传感器系统 |
| HSS | Hollow Structural Section | 空心结构截面 |
| HSS | Health And Social Services (Alaska) | 健康和社会服务（阿拉斯加州） |
| HSS | Hire Sales and Service | 雇佣销售和服务 |
| HSS | Home Service Store | 家庭服务商店 |
| HSS | High-Signal Select | 高信号选择 |
| HSS | Highly Sensitive System | 高灵敏系统 |
| HSS | Hollow Steel Section (steel) | 空心型钢（钢） |
| HSS | Historiae Societatis Socius (Fellow of the Historical Society) | 社会历史学会会员 |
| HSS | Home Subscriber Server | 家庭订户服务器 |
| HSS | Helicopter Support Ship | 直升机支援舰 |
| HSS | Hardware Support Specialist | 硬件支持专家 |
| HSS | hepatic stimulator substance | 肝刺激物质 |
| HSS | Health and Support Services | 健康和支持服务 |
| HSS | hora somni sumendus | 霍拉·索尼·苏门德斯 |
| HSS | Hrvatski Skijaški Savez (Croatian Ski Federation) | Hrvatski Skijaški Savez (Croatian Ski Federation) |
| HSS | henoch-schonlein syndrome | henoch-schonlein综合征 |
| HSS | High Speed Serial interface | 高速串行接口 |
| HSS | Hike Stalk Shoot | 徒步跟踪射击 |
| HSS | High Speed Serial | 高速串行 |
| HSS | Helmet Sight System | 头盔瞄准系统 |
| HSS | Hissar, India | 印度希萨尔 |
| HSS | Horizontal Stretch or Shrink | 水平拉伸或收缩 |
| HSS | Hrvatska Seljacka Stranka (Croatian Peasants Party) | Hrvatska Seljacka Stranka（克罗地亚农民党） |
| HSS | Hospital San Sebastian (Guatemala) | 圣塞巴斯蒂安医院（危地马拉） |
| HSS | High Speed Switch (Sonet) | 高速开关（Sonet） |
| HSS | Hollow Structural Section (AISC) | 空心结构截面（AISC） |
| HSS | High Speed Stability | 高速稳定性 |
| HSS | Heartland Senior Services | Heartland高级服务 |
| HSS | Humbucker-Single-Single (electric guitar pickup configuration) | Humbucker单曲（电吉他拾音器配置） |
| HSS | Hospital Shared Services | 医院共享服务 |
| HSS | Hepatic Support System (liver system) | 肝支持系统（肝系统） |
| HSS | Home Subscriber Server (3GPP) | 家庭订户服务器（3GPP） |
| HSS | High Spectral Sensor | 高光谱传感器 |
| HSS | Horizontal Stud Soderberg (aluminium production) | 索德堡卧式螺柱（铝生产） |
| HSS | Horizontal Store Support | 水平存储支持 |
| HSS | Health Screening System | 健康筛查系统 |
| HSS | High-Speed Serial | 高速串行 |
| HSS | Helensvale State School (Gold Coast, Australia) | 海伦斯维尔州立学校（澳大利亚黄金海岸） |
| HSS | Homer Simpson Syndrome (The Simpsons TV cartoon) | 霍默·辛普森综合征（《辛普森一家》电视动画片） |
| HSS | Headquarters Support System | 总部支持系统 |
| HSS | Hyper-Sonic Sound | 超音速声音 |
| HSS | Higher Strength Steel | 高强度钢 |