| FESC | Florida Education Standards Commission | 佛罗里达州教育标准委员会 |
| FESC | Federal Emergency Support Coordinator | 联邦紧急支持协调员 |
| FESC | Forward Electronic Service Center (aviation) | 前方电子服务中心（航空） |
| FESC | Federal Emergency Support Capability | 联邦应急支持能力 |
| FESC | Frente Estudiantil Social Cristiano | 社会科学界克里斯蒂亚诺 |
| FESC | Fellow of the European Stroke Council | 欧洲中风理事会成员 |
| FESC | Fellow of the European Society of Cardiology | 欧洲心脏病学会会员 |
| FESC | Framework for procuring External Support for Commissioners (UK) | 专员外部支持采购框架（英国） |
| FESC | Failure Effects Severity Classification (reliability) | 故障影响严重性分类（可靠性） |