| HIS | Home Information System | 家庭信息系统 |
| HIS | hospital information system | 医院信息系统 |
| HIS | Horizontal Situation Indicator | 水平位置指示 |
| HIS | Hlstidine | 组氨酸 |
| HIS | Hayman Island, Queensland, Australia - Hayman Island Airport (Airport Code) | 澳大利亚昆士兰州海曼岛-海曼岛机场（机场代码） |
| HIS | Health Information Services | 健康信息服务 |
| HIS | Hughes Information System | 休斯信息系统 |
| HIS | Health Informatics Service (UK NHS) | 健康信息服务（英国NHS） |
| HIS | Hypermedia Indexing Schema | 超媒体索引架构 |
| HIS | Hydraulic Institute Standards | 水力学会标准 |
| HIS | High Resolution Spectroscopy Mission | 高分辨率光谱学任务 |
| HIS | Hybrid Intelligent Systems (International Conference) | 混合智能系统（国际会议） |
| HIS | Hardware Intensive Systems | 硬件密集型系统 |
| HIS | Honeywell Information Systems, Incorporated | 霍尼韦尔信息系统公司 |
| HIS | Human Systems Integration | 人力系统综合 |
| HIS | Horeca Internet Services (Netherlands ISP) | Horeca互联网服务（荷兰ISP） |
| HIS | Heller Information Services | 海勒信息服务 |
| HIS | Host Integration Server (Microsoft) | 主机集成服务器（Microsoft） |
| HIS | HST Instrument Servicing | HST仪器维修 |
| HIS | Hearing Instrument Specialist | 听力仪器专家 |
| HIS | Hic Iacet Sepultus (Latin: here lies buried) | Hic Iacet Sepultus（拉丁语：此处埋葬） |
| HIS | Health Information System | 健康信息系统 |
| HIS | hyperimmunized suppressed | 超免疫抑制 |
| HIS | health interview survey | 健康访谈调查 |
| HIS | hyperimmune serum | 高免疫血清 |
| HIS | health care information system | 医疗保健信息系统 |
| HIS | Hiv Incidence Surveillance | Hiv发病率监测 |
| HIS | Home Internet Solution | 家庭互联网解决方案 |
| HIS | Histidine (Amino Acid) | 组氨酸（氨基酸） |
| HIS | High Intensity Signal | 高强度信号 |
| HIS | History of executing/ viewing/ editing | 历史上看/编辑/执行 |
| HIS | Hardman Information System | 哈德曼信息系统 |
| HIS | Hegazy Industrial Services | 霸道的工业服务 |
| HIS | Hayman Island, Queensland, Australia | 澳大利亚昆士兰州海曼岛 |
| HIS | Cigna High Income Shares | Cigna高收益股票 |
| HIS | Halt in Impossible State | 在不可能状态下停止 |
| HIS | Human Instruction Set | 人工指令集 |
| HIS | Harvard Islamic Society | 哈佛伊斯兰学会 |
| HIS | Hue, Intensity, Saturation (transformation) | 色调、强度、饱和度（变换） |
| HIS | Hardware Intensive Software | 硬件密集型软件 |
| HIS | Hiding in Shadows | 隐藏在阴影中 |
| HIS | Home Internet Service | 家庭互联网服务 |
| HIS | House Information System | 房屋信息系统 |
| HIS | Hyperspectral Imaging Spectroscopy | 高光谱成像光谱学 |
| HIS | Hrvatska Izvještajna Služba (Croatian Informing Service) | Hrvatska Izvještajna Služba (Croatian Informing Service) |
| HIS | High-Resolution Interferometer Spectrometer | 高分辨率干涉仪光谱仪 |
| HIS | Hostile Intelligence Service | 敌方情报处 |
| HIS | High-Infrared Spectrometer | 高红外光谱仪 |
| HIS | Houses of the Inner Sphere (MechWarrior) | 内球之家（机械战士） |
| HIS | Home Integration System | 家庭集成系统 |
| HIS | Hightech Information Systems Ltd | 高科技信息系统有限公司 |
| HIS | Home Improvement Specialist | 家庭改善专家 |
| HIS | Heidelberg International School | 海德堡国际学校 |
| HIS | High-Impedance Surface | 高阻抗表面 |
| HIS | HEED (Health, Education and Economic Development) International School (Bangladesh) | HEED（卫生、教育和经济发展）国际学校（孟加拉国） |
| HIS | Hakomi Integrative Somatics | Hakomi综合躯体学 |