| SPZ | Sanitary Protection Zone | 卫生防护区 |
| SPZ | SpiritZ (Runescape Clan) | SpiritZ（逃亡部落） |
| SPZ | Stephen P. Zeldes, Graduate School of Business Columbia University | Stephen P.Zeldes，哥伦比亚大学商学院研究生院 |
| SPZ | Ship Protection Zone | 船舶保护区 |
| SPZ | Source Protection Zone | 源保护区 |
| SPZ | South Park Zone (website) | 南公园区（网站） |
| SPZ | spätzle (dorsoventral patterning, genetics) | spätzle (dorsoventral patterning, genetics) |
| SPZ | Socionet Personal Zone | 社交网络个人区域 |
| SPZ | sulfinpyrazone(uricosuric) | 磺吡唑酮（尿酸） |
| SPZ | Spetsnaz | 斯佩茨纳兹 |
| SPZ | sulphaphenazole | 噻吩磺唑 |
| SPZ | Submarine Patrol Zone | 潜艇巡逻区 |
| SPZ | Special Promotion Zone | 特别促销区 |
| SPZ | SchÜtzenpanzer (German; armoured personnel carrier) | SchÜtzenpanzer (German; armoured personnel carrier) |
| SPZ | Stream Protection Zone | 河流保护区 |
| SPZ | Simplified Planning Zone | 简化规划区 |
| SPZ | Springdale, Arkansas | 阿肯色州斯普林代尔 |