| LION | Literature Online | 在线文学 |
| LION | Lithium Ion (battery) | 锂离子（电池） |
| LION | Library of Input/Output and Numerical Subroutines (UNIVAC 1107 assembly language) | 图书馆的输入/输出和数字子程序(UNIVAC 597汇编语言) |
| LION | Leading International Open Networkers | 领先的国际开放网络 |
| LION | Lenders Interactive Online Network | 贷方互动在线网络 |
| LION | Link Interoperability Network | 链路互操作性网络 |
| LION | Local Interagency Operations Network (Los Angeles County) | 当地机构间行动网络（洛杉矶县） |
| LION | Lightweight Infrared Observation Nightsight (thermal imaging camera from THALES Optronics, Netherlands) | 轻型红外观测夜视仪（来自荷兰泰雷兹光电公司的热成像相机） |
| LION | Labor Immigrant Organizing Network | 劳工移民组织网络 |
| LION | Librarians Information Online Network | 图书馆员信息在线网络 |
| LION | Fidelity National Corporation | 富达国家公司 |
| LION | LINC on NT (Asysco software migration tool) | NT上的LINC（Asysco软件迁移工具） |
| LION | Lynchburg Information Online Network | 林奇堡信息在线网络 |
| LION | Library Information On The Net | 网上图书馆信息 |
| LION | Linked In Open Networker | 链接到Open Networker |
| LION | Library Information Online Network | 图书馆信息在线网络 |
| LION | Low Energy Ion and Electron Instrument | 低能离子电子仪器 |