| PICO | Product Improvement Control Office | 产品改进控制办公室 |
| PICO | Patient Intervention Comparison Outcome | 患者干预比较结果 |
| PICO | Pervasive Information Community Organization | 普及信息社区组织 |
| PICO | Patient Intelligence Control Outlook | 患者智能控制展望 |
| PICO | Polio Information Center Online | 脊髓灰质炎信息中心在线 |
| PICO | Pre-Installation Check Out (equipment component testing prior to delivery) | 安装前检查（交付前的设备组件测试） |
| PICO | Person In Charge Of | 负责人： |
| PICO | Power Integrity Corporation | 电力完整性公司 |
| PICO | Personalizing, Informing, Communicating, and Organizing | 个性化、告知、沟通和组织 |
| PICO | Patient/Problem, Intervention, Comparison, Outcome (evidence-based medicine) | 病人/问题、干预,比较,结果(循证医学) |
| PICO | port in charterers option | 租船港选择权 |
| PICO | P I C O Holdings, Inc. | 太平洋控股有限公司。 |
| PICO | Polar Ice Coring Office | 极地冰芯办公室 |
| PICO | Patient Intervention Comparison And Outcome | 患者干预比较和结果 |
| PICO | PINE Composer | PINE作曲家 |
| PICO | Problems Into Challenges And Opportunities | 问题转化为挑战和机遇 |
| PICO | Plant Improvement Company Ltd (Okanagan Plant Improvement Corporation; Summerland, BC, Canada) | 植物改良有限公司（Okanagan植物改良公司；加拿大不列颠哥伦比亚省萨默兰市） |
| PICO | Person In Charge Of Olympiads | 奥运会负责人 |
| PICO | Program In Chip Out | 程序输入芯片输出 |
| PICO | Pacific Institute For Community Organization | 太平洋社区组织研究所 |