| LCO | London Chamber Orchestra | 伦敦室内乐队 |
| LCO | lethal concentration-0 | 安全浓度 |
| LCO | Launching Control Officer | 发射控制官 |
| LCO | Launch Control Officer | 发射控制官 |
| LCO | Labour Conciliation Officer | 劳动调解官 |
| LCO | Levine Communications Office (PR firm; Los Angeles, CA, USA) | 莱文通信办公室（公关公司；美国加利福尼亚州洛杉矶） |
| LCO | Local Compliance Officer | 当地合规官 |
| LCO | Lipo-Chitooligosaccharide | 脂壳寡糖 |
| LCO | Land Combat Operations | 陆地作战行动 |
| LCO | Liquid Crystal Oscillator | 液晶振荡器 |
| LCO | Late Check Out (lodging) | 延迟退房（住宿） |
| LCO | Lara Croft Online (gaming site) | Lara Croft在线（游戏网站） |
| LCO | Local Control Office | 当地控制办公室 |
| LCO | Loopback Command Off | 环回命令关闭 |
| LCO | Lague, Congo | 刚果拉格 |
| LCO | Life Cycle Objective | 生命周期目标 |
| LCO | Local Cable Operator | 本地电缆操作员 |
| LCO | Life Cycle Objectives (software development) | 生命周期目标（软件开发） |
| LCO | Launch Control Office(r) | 发射控制办公室（r） |
| LCO | Las Campanas Observatory (Chile) | 拉斯坎帕纳斯天文台（智利） |
| LCO | Lac Courte Oreilles (Wisconsin Native American Tribe) | Lac Courte Oreiles（威斯康辛州原住民部落） |
| LCO | Land Conservation Officer | 土地保护主任 |
| LCO | Local Census Office | 地方人口普查办公室 |
| LCO | Light Cycle Oil | 轻循环油 |
| LCO | Local Control Organization | 当地控制机构 |
| LCO | Limiting Condition of Operation | 操作限制条件 |
| LCO | Layered Cobalt Oxide | 层状氧化钴 |
| LCO | Limit Cycle Oscillation | 极限循环振荡 |
| LCO | Late Cornish (linguistics) | 晚康沃尔语（语言学） |
| LCO | Lawn Care Operation/Operator | 草坪护理操作算子 |
| LCO | Lighterage Control Officer | 打火机控制官 |
| LCO | Low Cost of Ownership | 低拥有成本 |
| LCO | Literal Change Operator | 文字更改运算符 |
| LCO | Leyssens & Co | Leyssens公司 |