| COST | Citizens Opposed to the SunCoast Tollway, Inc. (Florida) | 反对SunCoast Tollway公司的公民（佛罗里达州） |
| COST | Community Outreach Service Team | 社区外展服务队 |
| COST | Children Opposed To Smoking Tobacco | 反对吸烟的儿童 |
| COST | Costco Wholesale Corporation | 好市多公司 |
| COST | Contemporary Operations Studies Team | 当代运营研究团队 |
| COST | Common Object Support Toolkit | 通用对象支持工具包 |
| COST | Cooperation in the Field of Science and Technology Research (Europe) | 科学技术研究领域的合作（欧洲） |
| COST | Contracting Officer Support Tool | 合同官员支持工具 |
| COST | Committee on Science and Technology | 科学技术委员会 |
| COST | College of Saint Thomas (Fort Worth, Texas) | 圣托马斯学院（德克萨斯州沃思堡） |
| COST | Council on State Taxation | 国家税务委员会 |
| COST | Charlotteans Opposed to Sports Taxes (North Carolina) | 夏洛特人反对体育税（北卡罗来纳州） |
| COST | Council of Summer Theatres | 夏季剧院理事会 |
| COST | Church of Spiritual Technology | 精神技术教会 |