| HOC | Highest Outgoing Channel | 最高输出信道 |
| HOC | human ovarian cancer | 人卵巢癌 |
| HOC | Hogwarts On Crack | 霍格沃茨裂缝 |
| HOC | Komako, Papua New Guinea | 巴布亚新几内亚科马科 |
| HOC | Hurl On Completion | 完工时受伤 |
| HOC | Heap of Crap | 螃蟹堆 |
| HOC | Higher Order Crossing | 高阶交叉 |
| HOC | Home Ownership Center | 居者有其屋中心 |
| HOC | House Of Characters | 人物之家 |
| HOC | Hazardous Organic Constituents | 有害有机成分 |
| HOC | Hydrophobic Organic Compound | 疏水性有机化合物 |
| HOC | Hybrid Operational Control | 混合操作控制 |
| HOC | Hands-On Component | 实际操作组件 |
| HOC | Housing Opportunities Commission | 房屋机会委员会 |
| HOC | Holly Corporation | 霍利公司 |
| HOC | human intelligence operations cell (US DoD) | 人类情报行动小组（美国国防部） |
| HOC | Hurricane Operations Center | 飓风活动中心 |
| HOC | High Oil Corn (livestock) | 高油玉米（家畜） |
| HOC | Half Operational Capability | 一半作战能力 |
| HOC | History Of Coverage | 覆盖范围历史 |
| HOC | Head Of Component | 部件负责人 |
| HOC | Halogenated Organic Carbon | 卤化有机碳 |
| HOC | Head of Chancery | 大法官办公室主任 |
| HOC | Hydrophobic Organic Chemical | 疏水性有机化学品 |
| HOC | Hellenic Olympic Committee | 希腊奥委会 |
| HOC | House of Clairice | 克莱里斯家族 |
| HOC | Humanitarian Operations Center | 人道主义行动中心 |
| HOC | Halogenated Organic Compound | 卤化有机化合物 |
| HOC | Homepage of Chemometrics | 化学计量学主页 |
| HOC | Headquarters Operations Company (Army specific) | 总部作战连（陆军专用） |
| HOC | Higher Order Concern (writing) | 高阶关注（书面） |
| HOC | Heroes of Cybertron (Transformers, gaming) | 赛博坦英雄（变形金刚、游戏） |
| HOC | Hand of Conviction (gaming, EverQuest) | 定罪之手（游戏、EverQuest） |