| COSM | Coordinating Office of Shanghai Municipality | 上海市协调办公室 |
| COSM | Component Oriented Software Manufacturing | 面向组件的软件制造 |
| COSM | Common Open Service Market | 共同开放服务市场 |
| COSM | compound streptomycin | 复方链霉素 |
| COSM | clearance,osmolarity | 渗透压清除率 |
| COSM | combined otolaryngological spring meeting | 耳鼻喉科春季联合会议 |
| COSM | Counselors' Office of Shanghai Municipality | 上海市教务处 |
| COSM | Conference on Software Maintenance | 软件维护会议 |
| COSM | Composite Object Sound Modeling | 复合对象声音建模 |
| COSM | Composite Object Sound Modelling | 复合物体声音建模 |
| COSM | Customer Owned Sprint Maintained (Sprint) | 客户拥有的Sprint维护（Sprint） |
| COSM | Checkout, Services, and Maintenance (Airlock Equipment) | 检查、服务和维护（气闸设备） |