| NFL | National Forensic League | 全国法庭辩论联盟 |
| NFL | National Foresters League | 全国林业工作学者联盟 |
| NFL | National Film Library | 国家电影图书馆 |
| NFL | National Football League | 美国国家足球联盟,国家足球队 |
| NFL | nerve fiber layer | 神经纤维层 |
| NFL | non-fatty liver | 非脂肪肝 |
| NFL | New found land | 纽芬兰 |
| NFL | No-Fire Line | 射击安全线 |
| NFL | No Free Lunch | 没有免费午餐 |
| NFL | Not For Long | 不会很长时间 |
| NFL | New Foreign Launch (military launch detection) | 新的国外发射（军事发射探测） |
| NFL | Newfoundland (Canada) | 纽芬兰（加拿大） |
| NFL | National Federation of Labor | 全国劳工联合会 |
| NFL | New Found Love | 新发现的爱 |
| NFL | Neue FÜnf Länder (the states of former East Germany) | Neue FÜnf Länder (the states of former East Germany) |
| NFL | Noise Floor Level | 最低噪声水平 |
| NFL | NAS Fallon (Naval Air Station; Nevada) | NAS Fallon（内华达州海军航空站） |
| NFL | Non-Fermi Liquid | 非费米液体 |
| NFL | Navigation Feature Layer | 导航要素图层 |
| NFL | Not Freakin' Likely | “可能不会他妈的 |
| NFL | Norwegian Defence Industry Group | 挪威国防工业集团 |
| NFL | National Fat League | 全国脂肪联盟 |
| NFL | Nerd for Life | 终身的Nerd |
| NFL | Nuveen Insured Florida Premium Income Fund | Nuveen保险佛罗里达保费收入基金 |
| NFL | Needs For Living | 生活需求 |
| NFL | New Football League | 新足球联赛 |
| NFL | National Felon League | 全国重罪联盟 |
| NFL | Neighborhood Football League | 邻里足球联赛 |
| NFL | National Food League | 国家食品联盟 |
| NFL | National Forensics League | 全国法医联盟 |
| NFL | No Fan Loyalty | 没有粉丝忠诚度 |
| NFL | No Fun League | 没有乐趣联盟 |
| NFL | Not Fair Love | 不公平的爱 |
| NFL | No Friggin Life | 没有恐惧的生活 |
| NFL | Need For League | 联盟的需求 |
| NFL | No Fan Love | 没有粉丝的爱 |
| NFL | No Frisky Ladies | 没有弗里斯基女士 |
| NFL | Not For Law | 不适用于法律 |
| NFL | Not For The Light | 不是为了光 |
| NFL | National Fieldgoal League | 全国野球联赛 |
| NFL | National Felony League | 全国重罪联盟 |
| NFL | National Federation Of Law | 全国法律联合会 |