| IOC | Independent Operating Company | 自主营业公司 |
| IOC | International Oceanographic Commission | 国际海洋学委员会 |
| IOC | Intergovernmental Oceanographic Commission | 政府间海洋学委员会 |
| IOC | International Olympic Committee | 国际奥林匹克委员会 |
| IOC | Input.Output Channel | 输入/输出信道 |
| IOC | Input/Output Controller | 输入/输出控制器 |
| IOC | Integrated Optical Circuit | 集成光路 |
| IOC | INTELSAT Operations Center | 国际卫星组织操作中心 |
| IOC | InterOffice Channel | 局间信道 |
| IOC | Inversion of control | 反转控制 |
| IOC | Institute of Carpenters | 木匠协会 |
| IOC | IOTA Occultation Camera (International Occultation Timing Association) | IOTA掩星照相机（国际掩星计时协会） |
| IOC | Internet Operation Center | 互联网运营中心 |
| IOC | Independent Operating Carrier | 独立运营运营商 |
| IOC | Images-On-Call (teleradiology system) | 图像随叫随到（远程放射学系统） |
| IOC | Information Object Class | 信息对象类 |
| IOC | Inter-Office Channel | 办公室间通道 |
| IOC | Input Output Cabinet | 输入输出柜 |
| IOC | In-Orbit Construction (NASA) | 在轨建造（NASA） |
| IOC | Intergovernmental Oceanographic Commission (UNESCO) | 政府间海洋学委员会（教科文组织） |
| IOC | International Obesity Congress | 国际肥胖大会 |
| IOC | Instructor Orientation Course (SCUBA PADI course) | 教员入职培训课程（SCUBA PADI课程） |
| IOC | Intercell Ohmic Contact | 电池间欧姆接触 |
| IOC | Individual Oral Commentary | 个人口头评论 |
| IOC | ISDN Ordering Code (Bellcore) | ISDN订购码（Bellcore） |
| IOC | Immediate or Cancel (trade order) | 立即或取消（交易订单） |
| IOC | Internal Overload Control | 内部过载控制 |
| IOC | Internet Operations Center (IETF) | 互联网运营中心（IETF） |
| IOC | Inter-Organizational Coordination | 组织间协调 |
| IOC | Infantry Officers' Course (USMC) | 步兵军官课程(符合美国海军陆战队的) |
| IOC | Impact Over Cost | 对成本的影响 |
| IOC | Inter Office Communications | 办公室间通信 |
| IOC | Inter-Object Concurrency | 对象间并发 |
| IOC | Index of Cooperation (ITU-T) | 合作指数（ITU-T） |
| IOC | Internal Office Communication | 内部办公室沟通 |
| IOC | Interactive Orbit Calculator | 交互式动态观察计算器 |
| IOC | Internal Office Code | 内部办公室代码 |
| IOC | Indian Oil Corporation, Ltd | 印度石油公司 |
| IOC | Industrial Operations Command | 工业运转司令部 |
| IOC | Intrinsic Order Criterion | 内禀阶准则 |
| IOC | Information Operations Center | 信息运营中心 |
| IOC | Insist On Cash | 坚持现金 |
| IOC | In-Organic Contaminants | 有机污染物中 |
| IOC | ISDN Ordering Code | ISDN订购代码 |
| IOC | Impedance Of Circuit | 电路阻抗 |
| IOC | Inter- Office Channel | 办公室间通道 |
| IOC | Instead of Ordinary Coke | 代替普通可乐 |
| IOC | Inter-Office Communication | 办公室间通信 |
| IOC | Infantry Officer Course | 步兵军官课程 |
| IOC | Immediate Or Cancel | 立即或取消 |
| IOC | Incredibly Obvious Corruption | 难以置信的明显腐败 |
| IOC | Intolerant Olympic Committee | 不容忍奥林匹克委员会 |
| IOC | Integration, Organization, Cohesion | 整合、组织、凝聚力 |
| IOC | International Othello Competitors | 国际奥赛罗竞争对手 |
| IOC | Uluslararasi Olimpiyat Komitesi | Uluslararasi奥林匹克运动会 |
| IOC | Indoor Obstacle Course | 室内障碍物课程 |
| IOC | Indirect Object Clitic | 间接对象Clitic |
| IOC | Input/Output Comparator | 输入/输出对照 |
| IOC | Interesting Olympic Confederation | 有趣的奥林匹克联合会 |
| IOC | Institute of Organic Chemistry (China) | 有机化学研究所（中国） |
| IOC | In-Orbit Checkout | 动态观察检出 |
| IOC | Intraoperative Cholangiogram | 术中胆道造影 |
| IOC | Inorganic Chemical | 无机化学 |
| IOC | International Ozone Commission | 国际臭氧委员会 |
| IOC | Integrated Optical Component | 集成光学组件 |
| IOC | Innocent Owner/Operator Certificate | 无辜的人/操作证书 |
| IOC | Innovation Ontario Corporation (Government of Ontario Corporation) | 安大略省创新公司（安大略省政府公司） |
| IOC | Initial Operational Clearance | 初始运行许可 |
| IOC | Islam on Campus | 伊斯兰教在校园 |
| IOC | Initial Operational Capability | 初始作战能力 |
| IOC | International Oil Company | 国际石油公司 |
| IOC | Input/Output Cluster (Cray) | 输入/输出的聚类(哭) |
| IOC | In-Organic Chemical | 有机化学 |
| IOC | Indian Ocean Commission | 印度洋委员会 |
| IOC | Instantaneous Overcurrent | 瞬时过电流 |
| IOC | Inorganic Compound | 无机化合物 |
| IOC | Islamic Observation Centre | 伊斯兰观察中心 |
| IOC | Initial Operating Capability | 初始运行能力 |
| IOC | International Organized Crime | 国际有组织犯罪 |
| IOC | Instant ORGcharting! Organizational chart | 即时ORG图表！组织结构图 |
| IOC | Invasion Of Chaos | 混乱的入侵 |
| IOC | I'm Obviously Corrupt | 我显然腐败 |
| IOC | Imitation Of Christ | 模仿基督 |
| IOC | Inter-Organizational Council | 组织间理事会 |
| IOC | Intercept Operations Center | 拦截作战中心 |
| IOC | In-Organic Contaminant | 有机污染物中 |
| IOC | Infrastructure Operating Center | 基础设施运营中心 |
| IOC | Involuntary Outpatient Civil commitment | 非自愿门诊民事承诺 |
| IOC | Indian Ocean Climate | 印度洋气候 |
| IOC | Interfaith Open Communities | 宗教间开放社区 |
| IOC | Input/Output Configuration | 输入/输出配置 |
| IOC | Interception Of Communication | 通信拦截 |
| IOC | Inversion of Control (OOP pattern) | 控制反转（OOP模式） |
| IOC | Iteration On Coefficient | 迭代系数 |
| IOC | Incident Operations Center | 事故运营中心 |
| IOC | Index Of Cooperation | 合作指数 |
| IOC | Instrument Of Commitment | 承诺书 |
| IOC | Index Of Coincidence | 重合度指数 |