| OTF | on-the-fly | 高速数据传输错误纠正 |
| OTF | Over the Fence | 越过围栏 |
| OTF | On-Line Tax Form | 在线纳税表 |
| OTF | Optical Transfer Function | 光学传递函数 |
| OTF | On The Fly | 飞行中 |
| OTF | Orders To Fly | 飞行订单 |
| OTF | Open Token Foundation | 开放令牌基础 |
| OTF | Off Topic Forum | 非主题论坛 |
| OTF | Only the Facts | 只有事实 |
| OTF | Optimum Traffic Frequency | 最佳交通频率 |
| OTF | Optical Tunable Filter | 光学可调谐滤波器 |
| OTF | On the Floor (laughing) | 在地板上(笑) |
| OTF | Orders To Fire | 开火命令 |
| OTF | One True Friend | 一个真正的朋友 |
| OTF | Out the Front (automatic knife) | 离开前部(自动切刀) |
| OTF | Ontario Teachers' Federation (Canada) | 教师联合会(加拿大安大略省) |
| OTF | Objective Terrain Format (high resolution database format) | 目标地形格式(高分辨率数据库格式) |
| OTF | Ontario Trillium Foundation (Canada) | 安大略延龄草基金会(加拿大) |
| OTF | Optimized Thomas-Fermi | 优化Thomas Fermi |
| OTF | Object Testing Framework | 对象测试框架 |
| OTF | The Off Topic Forum | 非主题论坛 |
| OTF | Out The Front | 在前面 |
| OTF | Open Ttype Font File | 打开Ttype字体文件 |
| OTF | Operational Task Force | 作战任务组 |
| OTF | Of The Film | 电影中的 |
| OTF | Off The Floor | 离开地板 |
| OTF | Out Too Far | 出得太远 |
| OTF | Online Tax Filing | 网上报税 |
| OTF | Over Tecnology Fighter | 超技术战斗机 |
| OTF | Offender Tracking Form | 罪犯跟踪表 |
| OTF | Organ Transplant Fund | 器官移植基金 |
| OTF | OneTouchFootball (soccer discussion site) | OneTouchFootball(足球讨论网站) |
| OTF | One Time Fee | 一次性费用 |
| OTF | Open Telecommunications Framework (ECTF) | 开放电信框架(ECTF) |
| OTF | oral transfer factor | 口腔转移因子 |
| OTF | Over the Falls (surfing) | 飞越瀑布(冲浪) |
| OTF | Open Type Fonts (Adobe) | 开放式字体(Adobe) |
| OTF | On The Floor | 在地板上 |
| OTF | Operate to Failure (engineering maintenance strategy) | 故障操作(工程维护策略) |
| OTF | Off The Film (camera technology) | 离胶片(相机技术) |
| OTF | One Touch Financial | 一键理财 |
| OTF | Open Trace Format | 打开跟踪格式 |
| OTF | Out There Flapping | 在那里拍打 |
| OTF | Ohio Turfgrass Foundation | 俄亥俄州草坪草基金会 |
| OTF | Off the Front (cycling/racing slang) | 从前面(骑车/赛车俚语) |
| OTF | On-The-Fly (data acquisition method) | 飞行中(数据采集方法) |
| OTF | On the Phone (chat) | 在电话中(聊天) |
| OTF | Optimal Tower Field | 最佳塔场 |
| OTF | Optimal Tight Frame | 最佳紧密框架 |